A stochastic model for simulating ribosome kinetics in vivo.
Computational modelling of in vivo protein synthesis is highly complicated, as it requires the simulation of ribosomal movement over the entire transcriptome, as well as consideration of the concentration effects from 40+ different types of tRNAs and numerous other protein factors. Here I report on...
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-02-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1007618 |