Candida krusei pneumonia as a complication of a tuboovarian abscess treatment – case report
<p><strong>Background:</strong> Frequency of infections, caused by Candida glabrata and Candida krusei, which are more resistant to fluconazole, is increasing among hospitalised patients, especially among patients in intensive care units (ICU). Systemic Candida infections are parti...
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| Format: | Article |
| Language: | English |
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Slovenian Medical Association
2006-12-01
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| Series: | Zdravniški Vestnik |
| Subjects: | |
| Online Access: | http://vestnik.szd.si/index.php/ZdravVest/article/view/2057 |
| _version_ | 1811338999358291968 |
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| author | Jasna Uranjek Darja Kasnik |
| author_facet | Jasna Uranjek Darja Kasnik |
| author_sort | Jasna Uranjek |
| collection | DOAJ |
| description | <p><strong>Background:</strong> Frequency of infections, caused by Candida glabrata and Candida krusei, which are more resistant to fluconazole, is increasing among hospitalised patients, especially among patients in intensive care units (ICU). Systemic Candida infections are particularly dangerous. Pneumonia, caused by Candida species, most commonly albicans, rarely others, is a serious infection especially for immunocompromised patients. It’s often fatal. We present a case report of a serious lung infection with fluconazole resistant Candida krusei in a 42-year-old previously healthy patient with perforated tuboovarian abscess (TOA), consecutive severe sepsis and septic shock. Patient used intrauterine device (IUD) for 17 years without any gynaecological controls. Ascending genital infection with E.colli and Staph. chromogenes led to TOA. In spite of empirical antibiotic treatment, surgical and intensive care supportive therapy of affected organs, patient’s condition critically deteriorated until exact fungus specification was made and specific antifungal therapy for Candida krusei with voriconazol was started. After that patient’s condition improved.</p><p><strong>Conclusions:</strong> Connection between patient’s age, IUD use duration and severity of the pelvic inflammatory disease (PID) was seen as multiorgan septic dysfunction with dominant lung failure. Candida pneumonia is rare with non-neutropenic patients. Especially with »non albicans« species. We believe Candida krusei infection in our patient is related to general weakness and immunocompromised condition because of prolonged and severe PID. Candida krusei infection needs immediate specific antifungal treatment. It was the first Candida krusei infection in our ICU.</p> |
| first_indexed | 2024-04-13T18:18:43Z |
| format | Article |
| id | doaj.art-4716d08022a84d398a706abc0678dea1 |
| institution | Directory Open Access Journal |
| issn | 1318-0347 1581-0224 |
| language | English |
| last_indexed | 2024-04-13T18:18:43Z |
| publishDate | 2006-12-01 |
| publisher | Slovenian Medical Association |
| record_format | Article |
| series | Zdravniški Vestnik |
| spelling | doaj.art-4716d08022a84d398a706abc0678dea12022-12-22T02:35:32ZengSlovenian Medical AssociationZdravniški Vestnik1318-03471581-02242006-12-0175121545Candida krusei pneumonia as a complication of a tuboovarian abscess treatment – case reportJasna UranjekDarja Kasnik<p><strong>Background:</strong> Frequency of infections, caused by Candida glabrata and Candida krusei, which are more resistant to fluconazole, is increasing among hospitalised patients, especially among patients in intensive care units (ICU). Systemic Candida infections are particularly dangerous. Pneumonia, caused by Candida species, most commonly albicans, rarely others, is a serious infection especially for immunocompromised patients. It’s often fatal. We present a case report of a serious lung infection with fluconazole resistant Candida krusei in a 42-year-old previously healthy patient with perforated tuboovarian abscess (TOA), consecutive severe sepsis and septic shock. Patient used intrauterine device (IUD) for 17 years without any gynaecological controls. Ascending genital infection with E.colli and Staph. chromogenes led to TOA. In spite of empirical antibiotic treatment, surgical and intensive care supportive therapy of affected organs, patient’s condition critically deteriorated until exact fungus specification was made and specific antifungal therapy for Candida krusei with voriconazol was started. After that patient’s condition improved.</p><p><strong>Conclusions:</strong> Connection between patient’s age, IUD use duration and severity of the pelvic inflammatory disease (PID) was seen as multiorgan septic dysfunction with dominant lung failure. Candida pneumonia is rare with non-neutropenic patients. Especially with »non albicans« species. We believe Candida krusei infection in our patient is related to general weakness and immunocompromised condition because of prolonged and severe PID. Candida krusei infection needs immediate specific antifungal treatment. It was the first Candida krusei infection in our ICU.</p>http://vestnik.szd.si/index.php/ZdravVest/article/view/2057candida kruseivoriconazolpelvic inflammatory diseasepneumoniaintrauterine device |
| spellingShingle | Jasna Uranjek Darja Kasnik Candida krusei pneumonia as a complication of a tuboovarian abscess treatment – case report Zdravniški Vestnik candida krusei voriconazol pelvic inflammatory disease pneumonia intrauterine device |
| title | Candida krusei pneumonia as a complication of a tuboovarian abscess treatment – case report |
| title_full | Candida krusei pneumonia as a complication of a tuboovarian abscess treatment – case report |
| title_fullStr | Candida krusei pneumonia as a complication of a tuboovarian abscess treatment – case report |
| title_full_unstemmed | Candida krusei pneumonia as a complication of a tuboovarian abscess treatment – case report |
| title_short | Candida krusei pneumonia as a complication of a tuboovarian abscess treatment – case report |
| title_sort | candida krusei pneumonia as a complication of a tuboovarian abscess treatment case report |
| topic | candida krusei voriconazol pelvic inflammatory disease pneumonia intrauterine device |
| url | http://vestnik.szd.si/index.php/ZdravVest/article/view/2057 |
| work_keys_str_mv | AT jasnauranjek candidakruseipneumoniaasacomplicationofatuboovarianabscesstreatmentcasereport AT darjakasnik candidakruseipneumoniaasacomplicationofatuboovarianabscesstreatmentcasereport |