Signs and symptoms of developmental abnormalities of the genitourinary tract
Abstract Objective: The abnormalities of the genitourinary tract development are the leading cause of chronic kidney disease (CKD) in children. The diagnosis of this disease in Brazil is late and incomplete, which results in increased morbidity and mortality in this age group. Early diagnosis of th...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-06-01
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| Series: | Jornal de Pediatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572016000400057&lng=en&tlng=en |
| _version_ | 1818434701766950912 |
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| author | Paulo Cesar Koch Nogueira Isabel de Pádua Paz |
| author_facet | Paulo Cesar Koch Nogueira Isabel de Pádua Paz |
| author_sort | Paulo Cesar Koch Nogueira |
| collection | DOAJ |
| description | Abstract Objective: The abnormalities of the genitourinary tract development are the leading cause of chronic kidney disease (CKD) in children. The diagnosis of this disease in Brazil is late and incomplete, which results in increased morbidity and mortality in this age group. Early diagnosis of this condition is the prerogative of generalist pediatricians, and the aim of this study was to review the clinical signs and symptoms associated with developmental abnormalities of the genitourinary tract. Data sources: Based on the description of a symbolic clinical case, the authors conducted a non-systematic review of medical literature. Data synthesis: The results suggest that the following data should be used as a warning for early diagnosis of affected children: (a) combined urinary tract abnormalities (chromosomal abnormalities; sequence of malformations [VACTERLand Prune-Belly]; and musculoskeletal, digestive tract, heart, and nervous system malformations); (b) previous history (congenital anomalies of the kidney and urinary tract [CAKUT] in the family, low birth weight, and oligoamnios); (c) clinical signs (polyuria/nocturia, urinary tract infection, systemic arterial hypertension, failure to thrive, weak urinary stream, difficulty to start urination, distended bladder, non-monosymptomatic enuresis, urinary/urge incontinence, and bowel and bladder dysfunction); and (d) pre- and postnatal ultrasonographic alterations (increased anteroposterior diameter of the renal pelvis, mainly in the third trimester of pregnancy; single kidney; hydronephrosis associated with other abnormalities; and hydronephrosis with parenchymal involvement in the post-neonatal assessment). Conclusion: The suggestions shown here can help the pediatrician to establish clinical hypotheses for the early diagnosis of developmental abnormalities of the genitourinary tract without resorting to expensive and invasive procedures. |
| first_indexed | 2024-12-14T16:41:11Z |
| format | Article |
| id | doaj.art-471cc147baed4f8789d4a59ec0303f21 |
| institution | Directory Open Access Journal |
| issn | 1678-4782 |
| language | English |
| last_indexed | 2024-12-14T16:41:11Z |
| publishDate | 2016-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Jornal de Pediatria |
| spelling | doaj.art-471cc147baed4f8789d4a59ec0303f212022-12-21T22:54:19ZengElsevierJornal de Pediatria1678-47822016-06-01923 suppl 1576310.1016/j.jped.2016.01.006S0021-75572016000400057Signs and symptoms of developmental abnormalities of the genitourinary tractPaulo Cesar Koch NogueiraIsabel de Pádua PazAbstract Objective: The abnormalities of the genitourinary tract development are the leading cause of chronic kidney disease (CKD) in children. The diagnosis of this disease in Brazil is late and incomplete, which results in increased morbidity and mortality in this age group. Early diagnosis of this condition is the prerogative of generalist pediatricians, and the aim of this study was to review the clinical signs and symptoms associated with developmental abnormalities of the genitourinary tract. Data sources: Based on the description of a symbolic clinical case, the authors conducted a non-systematic review of medical literature. Data synthesis: The results suggest that the following data should be used as a warning for early diagnosis of affected children: (a) combined urinary tract abnormalities (chromosomal abnormalities; sequence of malformations [VACTERLand Prune-Belly]; and musculoskeletal, digestive tract, heart, and nervous system malformations); (b) previous history (congenital anomalies of the kidney and urinary tract [CAKUT] in the family, low birth weight, and oligoamnios); (c) clinical signs (polyuria/nocturia, urinary tract infection, systemic arterial hypertension, failure to thrive, weak urinary stream, difficulty to start urination, distended bladder, non-monosymptomatic enuresis, urinary/urge incontinence, and bowel and bladder dysfunction); and (d) pre- and postnatal ultrasonographic alterations (increased anteroposterior diameter of the renal pelvis, mainly in the third trimester of pregnancy; single kidney; hydronephrosis associated with other abnormalities; and hydronephrosis with parenchymal involvement in the post-neonatal assessment). Conclusion: The suggestions shown here can help the pediatrician to establish clinical hypotheses for the early diagnosis of developmental abnormalities of the genitourinary tract without resorting to expensive and invasive procedures.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572016000400057&lng=en&tlng=enMalformação do trato urinárioDoença renal crônicaDiagnóstico precoceCriança |
| spellingShingle | Paulo Cesar Koch Nogueira Isabel de Pádua Paz Signs and symptoms of developmental abnormalities of the genitourinary tract Jornal de Pediatria Malformação do trato urinário Doença renal crônica Diagnóstico precoce Criança |
| title | Signs and symptoms of developmental abnormalities of the genitourinary tract |
| title_full | Signs and symptoms of developmental abnormalities of the genitourinary tract |
| title_fullStr | Signs and symptoms of developmental abnormalities of the genitourinary tract |
| title_full_unstemmed | Signs and symptoms of developmental abnormalities of the genitourinary tract |
| title_short | Signs and symptoms of developmental abnormalities of the genitourinary tract |
| title_sort | signs and symptoms of developmental abnormalities of the genitourinary tract |
| topic | Malformação do trato urinário Doença renal crônica Diagnóstico precoce Criança |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572016000400057&lng=en&tlng=en |
| work_keys_str_mv | AT paulocesarkochnogueira signsandsymptomsofdevelopmentalabnormalitiesofthegenitourinarytract AT isabeldepaduapaz signsandsymptomsofdevelopmentalabnormalitiesofthegenitourinarytract |