Dietary Vitamin B6 Deficiency Impairs Gut Microbiota and Host and Microbial Metabolites in Rats

Dietary Vitamin B6 Deficiency Impairs Gut Microbiota and Host and Microbial Metabolites in Rats

Vitamin B6 plays a crucial role as a cofactor in various enzymatic reactions but bacteria-produced vitamin B6 is not sufficient to meet host requirements. Our objective was to assess the impact of diet-derived vitamin B6 on gut microbiota and host serum metabolomics. Sprague–Dawley rats (<i>n&...

Full description

Bibliographic Details
Main Authors:	Shyamchand Mayengbam, Faye Chleilat, Raylene A. Reimer
Format:	Article
Language:	English
Published:	MDPI AG 2020-11-01
Series:	Biomedicines
Subjects:	vitamin B6 pyridoxal gut microbiota metabolomics sex effect
Online Access:	https://www.mdpi.com/2227-9059/8/11/469

Similar Items

Effects of maternal vitamin deficiency on the microstructure of the maternal hippocampus and behavior in offspring
by: Ashwija Shetty, Msc, et al.
Published: (2023-10-01)

B Vitamins and Their Roles in Gut Health
by: Khandkar Shaharina Hossain, et al.
Published: (2022-06-01)

Synthesis of B6 vitamin
by: Vučijak Nevena Ž., et al.
Published: (2009-01-01)

Dietary Reference Values for vitamin B6
by: EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
Published: (2016-06-01)

MOLECULAR MECHANISMS UNDERLYING THERAPEUTIC ACTION OF VITAMIN B6
by: O. A. Zagubnaya, et al.
Published: (2023-02-01)

A one-step NIST traceable HPLC method for quantitation of vitamin B6 and 4-pyridoxic acid in human plasma
by: Xiaochun Zhang, et al.
Published: (2020-08-01)

Associations of serum vitamin B6 status with the risks of cardiovascular, cancer, and all-cause mortality in the elderly
by: Pengxi Wang, et al.
Published: (2024-04-01)

A Novel Two-Dimensional Liquid Chromatography Combined with Ultraviolet Detection Method for Quantitative Determination of Pyridoxal 5′-Phosphate, 4-Pyridoxine Acid and Pyridoxal in Animal Plasma
by: Rong-Ju Yang, et al.
Published: (2023-04-01)

Association of Plasma Vitamin B6 With Coronary Heart Disease in Patients Undergoing Diagnostic Coronary Angiography: New Insight on Sex Differences
by: Lihua Hu, et al.
Published: (2021-12-01)

Vitamin B1 and B6 in the malaria parasite: requisite or dispensable?
by: C. Wrenger, et al.
Published: (2008-02-01)

Vitamin B1 and B6 in the malaria parasite: requisite or dispensable?
by: C. Wrenger, et al.

Prediction of vitamin interacting residues in a vitamin binding protein using evolutionary information
by: Panwar Bharat, et al.
Published: (2013-02-01)

Vitamin B6: A Long Known Compound of Surprising Complexity
by: Sutton Mooney, et al.
Published: (2009-01-01)

The Parkinson’s Disease Death Rate: Carbidopa and Vitamin B6 [Retraction]
by: Hinz M, et al.
Published: (2021-03-01)

The Therapeutic Potential of Vitamins B1, B3 and B6 in Charcot–Marie–Tooth Disease with the Compromised Status of Vitamin-Dependent Processes
by: Victoria Bunik
Published: (2023-06-01)

The Parkinson’s Disease Death Rate: Carbidopa and Vitamin B6 [Expression of Concern]
by: Hinz M, et al.
Published: (2020-04-01)

The Relationship Between Vitamin B6, Diabetes and Cancer
by: Chiara Merigliano, et al.
Published: (2018-09-01)

Parkinson’s Disease: Carbidopa, Nausea, and Dyskinesia [Retraction]
by: Hinz M, et al.
Published: (2021-03-01)

Cloning and Characterization of Pyridoxal Kinase from Geobacillus sp. H6a
by: Jumnong Pasri, et al.
Published: (2022-03-01)

Parkinson’s Disease: Carbidopa, Nausea, and Dyskinesia [Expression of Concern]
by: Hinz M, et al.
Published: (2020-04-01)

Scientific opinion on the tolerable upper intake level for vitamin B6
by: EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), et al.
Published: (2023-05-01)

Circulating pyridoxal 5′-phosphate in serum and whole blood: implications for assessment of vitamin B6 status
by: Obeid Rima, et al.
Published: (2023-02-01)

Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5′‐Phosphate Level With Depression in US Adults: Findings From NHANES 2005–2010
by: Jinhong Lu, et al.
Published: (2024-11-01)

The role of vitamers and dietary-based metabolites of vitamin D in prevention of vitamin D deficiency
by: Kevin D. Cashman
Published: (2012-04-01)

7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase
by: Marian Brenner, et al.
Published: (2024-06-01)

Sex-Specific Catabolic Metabolism Alterations in the Critically Ill following High Dose Vitamin D
by: Sowmya Chary, et al.
Published: (2022-02-01)

Structural Dynamics and Perspectives of Vitamin B6 Biosynthesis Enzymes in Plasmodium: Advances and Open Questions
by: Angélica Luana C. Barra, et al.
Published: (2021-07-01)

Theoretical Insights into Different Complexation Modes of Dioxovanadium(V) Compounds with Pyridoxal Semicarbazone/Thiosemicarbazone/S-Methyl-iso-thiosemicarbazone Ligands
by: Odeh Abdullah Odeh Alshammari, et al.
Published: (2024-03-01)

Dietary fibers boost gut microbiota-produced B vitamin pool and alter host immune landscape
by: Erica T. Grant, et al.
Published: (2024-09-01)

4-Pyridoxic Acid/Pyridoxine Ratio in Patients with Type 2 Diabetes is Related to Global Cardiovascular Risk Scores
by: Rima Obeid, et al.
Published: (2019-03-01)

Vitamin B6 Acquisition and Metabolism in Schistosoma mansoni
by: Akram A. Da’dara, et al.
Published: (2021-02-01)

The PdxR-PdxKU locus involved in vitamin B6 salvage is important for group A streptococcal resistance to neutrophil killing and survival in human blood
by: Sarah E. Davis, et al.
Published: (2024-12-01)

A loss of Pdxk model of Parkinson disease in Drosophila can be suppressed by Buffy
by: P. Githure M’Angale, et al.
Published: (2017-06-01)

Inhibiting Pyridoxal Kinase of Entamoeba histolytica Is Lethal for This Pathogen
by: Suneeta Devi, et al.
Published: (2021-04-01)

Dietary and Microbial Metabolites in the Regulation of Host Immunity
by: Naoko Shibata, et al.
Published: (2017-11-01)

Association between serum pyridoxal 5′-phosphate levels and chronic obstructive pulmonary disease: findings based on NHANES 2005–2010
by: Yanbin Liu, et al.
Published: (2025-01-01)

Synthesis of [13C3]-B6 Vitamers Labelled at Three Consecutive Positions Starting from [13C3]-Propionic Acid
by: Thomas Bachmann, et al.
Published: (2018-08-01)

Essential Metabolic Routes as a Way to ESKAPE From Antibiotic Resistance
by: Angélica Luana C. Barra, et al.
Published: (2020-02-01)

Gut Microbiota and Fecal Metabolites Associated With Neurocognitive Impairment in HIV-Infected Population
by: Ruihua Dong, et al.
Published: (2021-10-01)

In vitro oxidation of aldehyde oxidase from rabbit liver: Specificity toward endogenous substrates
by: Khaled S. Al salhen
Published: (2014-01-01)