Macrophage immunomodulatory activity of Acanthopanax senticousus polysaccharide nanoemulsion via activation of P65/JNK/ikkαsignaling pathway and regulation of Th1/Th2 Cytokines

Macrophage immunomodulatory activity of Acanthopanax senticousus polysaccharide nanoemulsion via activation of P65/JNK/ikkαsignaling pathway and regulation of Th1/Th2 Cytokines

Nanoemulsions (NE) are used widely in pharmaceutical drug formulations and vaccine preparation, and Acanthopanax senticousus polysaccharide (ASPS) is a natural bioactive compound with immunostimulatory activity. Therefore, NE-loaded ASPS is expected to provide immunological enhancement for effective...

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Bibliographic Details
Main Authors: Xianghui Li, Zhiqiang Zhang, Zhenhuan Guo, Li Zhao, Yonglu Liu, Xia Ma, Qigai He
Format: Article
Language:English
Published: PeerJ Inc. 2021-12-01
Series:PeerJ
Subjects:
Nanoemulsion
Acanthopanax senticosus polysaccharide
Immune responses
T lymphocyte
Pseudo-ternary phase diagram
Online Access:https://peerj.com/articles/12575.pdf

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