Mapping the Salinity Gradient in a Microfluidic Device with Schlieren Imaging

This work presents the use of the schlieren imaging to quantify the salinity gradients in a microfluidic device. By partially blocking the back focal plane of the objective lens, the schlieren microscope produces an image with patterns that correspond to spatial derivative of refractive index in the...

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Main Authors: Chen-li Sun, Shao-Tuan Chen, Po-Jen Hsiao
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/15/5/11587
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author Chen-li Sun
Shao-Tuan Chen
Po-Jen Hsiao
author_facet Chen-li Sun
Shao-Tuan Chen
Po-Jen Hsiao
author_sort Chen-li Sun
collection DOAJ
description This work presents the use of the schlieren imaging to quantify the salinity gradients in a microfluidic device. By partially blocking the back focal plane of the objective lens, the schlieren microscope produces an image with patterns that correspond to spatial derivative of refractive index in the specimen. Since salinity variation leads to change in refractive index, the fluid mixing of an aqueous salt solution of a known concentration and water in a T-microchannel is used to establish the relation between salinity gradients and grayscale readouts. This relation is then employed to map the salinity gradients in the target microfluidic device from the grayscale readouts of the corresponding micro-schlieren image. For saline solution with salinity close to that of the seawater, the grayscale readouts vary linearly with the salinity gradient, and the regression line is independent of the flow condition and the salinity of the injected solution. It is shown that the schlieren technique is well suited to quantify the salinity gradients in microfluidic devices, for it provides a spatially resolved, non-invasive, full-field measurement.
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spelling doaj.art-4730cb311d8f4229a29bfab9910a330b2022-12-22T02:57:14ZengMDPI AGSensors1424-82202015-05-01155115871160010.3390/s150511587s150511587Mapping the Salinity Gradient in a Microfluidic Device with Schlieren ImagingChen-li Sun0Shao-Tuan Chen1Po-Jen Hsiao2Department of Mechanical Engineering, National Taiwan University, 1 Roosevelt Road Section 4, Taipei 10617, TaiwanDepartment of Mechanical Engineering, National Taiwan University, 1 Roosevelt Road Section 4, Taipei 10617, TaiwanDepartment of Mechanical Engineering, National Taiwan University, 1 Roosevelt Road Section 4, Taipei 10617, TaiwanThis work presents the use of the schlieren imaging to quantify the salinity gradients in a microfluidic device. By partially blocking the back focal plane of the objective lens, the schlieren microscope produces an image with patterns that correspond to spatial derivative of refractive index in the specimen. Since salinity variation leads to change in refractive index, the fluid mixing of an aqueous salt solution of a known concentration and water in a T-microchannel is used to establish the relation between salinity gradients and grayscale readouts. This relation is then employed to map the salinity gradients in the target microfluidic device from the grayscale readouts of the corresponding micro-schlieren image. For saline solution with salinity close to that of the seawater, the grayscale readouts vary linearly with the salinity gradient, and the regression line is independent of the flow condition and the salinity of the injected solution. It is shown that the schlieren technique is well suited to quantify the salinity gradients in microfluidic devices, for it provides a spatially resolved, non-invasive, full-field measurement.http://www.mdpi.com/1424-8220/15/5/11587salinity gradientmicroscale schlieren techniquemicrofluidicquantitative analysis
spellingShingle Chen-li Sun
Shao-Tuan Chen
Po-Jen Hsiao
Mapping the Salinity Gradient in a Microfluidic Device with Schlieren Imaging
Sensors
salinity gradient
microscale schlieren technique
microfluidic
quantitative analysis
title Mapping the Salinity Gradient in a Microfluidic Device with Schlieren Imaging
title_full Mapping the Salinity Gradient in a Microfluidic Device with Schlieren Imaging
title_fullStr Mapping the Salinity Gradient in a Microfluidic Device with Schlieren Imaging
title_full_unstemmed Mapping the Salinity Gradient in a Microfluidic Device with Schlieren Imaging
title_short Mapping the Salinity Gradient in a Microfluidic Device with Schlieren Imaging
title_sort mapping the salinity gradient in a microfluidic device with schlieren imaging
topic salinity gradient
microscale schlieren technique
microfluidic
quantitative analysis
url http://www.mdpi.com/1424-8220/15/5/11587
work_keys_str_mv AT chenlisun mappingthesalinitygradientinamicrofluidicdevicewithschlierenimaging
AT shaotuanchen mappingthesalinitygradientinamicrofluidicdevicewithschlierenimaging
AT pojenhsiao mappingthesalinitygradientinamicrofluidicdevicewithschlierenimaging