Maternal effect genes as risk factors for congenital heart defects

Maternal effect genes as risk factors for congenital heart defects

Summary: Maternal effect genes (MEGs) encode factors (e.g., RNA) in the oocyte that control embryonic development prior to activation of the embryonic genome. Over 80 mammalian MEGs have been identified, including several that have been associated with phenotypes in humans. Maternal variation in MEG...

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Bibliographic Details
Main Authors: Fadi I. Musfee, Omobola O. Oluwafemi, A.J. Agopian, Hakon Hakonarson, Elizabeth Goldmuntz, Laura E. Mitchell
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:HGG Advances
Subjects:
association
congenital
heart
gene
gene set
malformation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247722000148

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