Lactobacillus Intestinalis Primes Epithelial Cells to Suppress Colitis‐Related Th17 Response by Host‐Microbe Retinoic Acid Biosynthesis

Lactobacillus Intestinalis Primes Epithelial Cells to Suppress Colitis‐Related Th17 Response by Host‐Microbe Retinoic Acid Biosynthesis

Abstract Gut microbiome is integral to the pathogenesis of ulcerative colitis. A novel probiotic Lactobacillus intestinalis (L. intestinalis) exerts a protective effect against dextran sodium sulfate‐induced colitis in mice. Based on flow cytometry, colitis‐associated Th17 cells are the target of L....

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Bibliographic Details
Main Authors: Qi‐Wen Wang, Ding‐Jia‐Cheng Jia, Jia‐Min He, Yong Sun, Yun Qian, Qi‐Wei Ge, Ya‐Dong Qi, Qing‐Yi Wang, Ying‐Ying Hu, Lan Wang, Yan‐Fei Fang, Hui‐Qin He, Man Luo, Li‐Jun Feng, Jian‐Min Si, Zhang‐Fa Song, Liang‐Jing Wang, Shu‐Jie Chen
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Advanced Science
Subjects:
colitis
microbes
retinoic acid
Th17
Online Access:https://doi.org/10.1002/advs.202303457

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