Apocynin Attenuates Diabetes-Induced Skeletal Muscle Dysfunction by Mitigating ROS Generation and Boosting Antioxidant Defenses in Fast-Twitch and Slow-Twitch Muscles

Apocynin Attenuates Diabetes-Induced Skeletal Muscle Dysfunction by Mitigating ROS Generation and Boosting Antioxidant Defenses in Fast-Twitch and Slow-Twitch Muscles

In response to diabetes mellitus, skeletal muscle is negatively affected, as is evident by reduced contractile force production, increased muscle fatigability, and increased levels of oxidative stress biomarkers. Apocynin is a widely used NADPH oxidase inhibitor, with antioxidant and anti-inflammato...

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Bibliographic Details
Main Authors: Sarai Sánchez-Duarte, Rocío Montoya-Pérez, Sergio Márquez-Gamiño, Karla S. Vera-Delgado, Cipriana Caudillo-Cisneros, Fernando Sotelo-Barroso, Luis A. Sánchez-Briones, Elizabeth Sánchez-Duarte
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Life
Subjects:
diabetes
skeletal muscle
NADPH oxidases
apocynin
oxidative stress
Online Access:https://www.mdpi.com/2075-1729/12/5/674

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