Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases

Abstract Background Malignant ‘triton’ tumor is an extremely rare subtype of malignant periphery nerve sheath tumors. Clinical diagnosis of malignant triton tumor is difficult before surgery due to its low incidence and the lack of knowledge. Therefore, to describe and summarize the CT imaging chara...

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Main Authors: Yuan Li, Qiling Peng, Ning Jiang, David P. Molloy, Chun Zeng, Qingchen Wu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Medical Imaging
Subjects:
Online Access:https://doi.org/10.1186/s12880-022-00848-9
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author Yuan Li
Qiling Peng
Ning Jiang
David P. Molloy
Chun Zeng
Qingchen Wu
author_facet Yuan Li
Qiling Peng
Ning Jiang
David P. Molloy
Chun Zeng
Qingchen Wu
author_sort Yuan Li
collection DOAJ
description Abstract Background Malignant ‘triton’ tumor is an extremely rare subtype of malignant periphery nerve sheath tumors. Clinical diagnosis of malignant triton tumor is difficult before surgery due to its low incidence and the lack of knowledge. Therefore, to describe and summarize the CT imaging characteristics of malignant triton tumor is of great assistance for early and preoperative diagnosis. Case presentation Two cases suspected of MTT by CT scan before operation were closely observed. The diagnosis of malignant triton tumor was eventually confirmed by immunochemical assay, which verified speculation of CT scans. Huge, irregular, well-circumscribed lobulated mass-like shadows can be observed from these patients by CT scans. Besides, heterogeneity of density within the body of tumor was well-established by CT scans, together with linear septum. Meanwhile, CT scans demonstrated that calcifications were remarkable at the margin of tumor body. Conclusions Some CT image features from two cases were presented as a reference for the preoperative consideration of MTT: (i) enormity of mass-like shadow; (ii) presence of well-circumscribed lobulated shape; (iii) septum within the well-defined mass accompanied with hemorrhage, necrosis and cystic changes as well as calcification, especially within neurofibromatosis type 1 patients.
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spelling doaj.art-47486eba2b5e4e8292c99ea2f12919a32022-12-22T00:42:06ZengBMCBMC Medical Imaging1471-23422022-07-012211610.1186/s12880-022-00848-9Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two casesYuan Li0Qiling Peng1Ning Jiang2David P. Molloy3Chun Zeng4Qingchen Wu5Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeSchool of Basic Medical Science, Chongqing Medical UniversityDepartment of Pathology, Chongqing Medical UniversitySchool of Basic Medical Science, Chongqing Medical UniversityDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical UniversityDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical UniversityAbstract Background Malignant ‘triton’ tumor is an extremely rare subtype of malignant periphery nerve sheath tumors. Clinical diagnosis of malignant triton tumor is difficult before surgery due to its low incidence and the lack of knowledge. Therefore, to describe and summarize the CT imaging characteristics of malignant triton tumor is of great assistance for early and preoperative diagnosis. Case presentation Two cases suspected of MTT by CT scan before operation were closely observed. The diagnosis of malignant triton tumor was eventually confirmed by immunochemical assay, which verified speculation of CT scans. Huge, irregular, well-circumscribed lobulated mass-like shadows can be observed from these patients by CT scans. Besides, heterogeneity of density within the body of tumor was well-established by CT scans, together with linear septum. Meanwhile, CT scans demonstrated that calcifications were remarkable at the margin of tumor body. Conclusions Some CT image features from two cases were presented as a reference for the preoperative consideration of MTT: (i) enormity of mass-like shadow; (ii) presence of well-circumscribed lobulated shape; (iii) septum within the well-defined mass accompanied with hemorrhage, necrosis and cystic changes as well as calcification, especially within neurofibromatosis type 1 patients.https://doi.org/10.1186/s12880-022-00848-9Computed tomographyMalignant triton tumorPresumptive diagnosisCase report
spellingShingle Yuan Li
Qiling Peng
Ning Jiang
David P. Molloy
Chun Zeng
Qingchen Wu
Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
BMC Medical Imaging
Computed tomography
Malignant triton tumor
Presumptive diagnosis
Case report
title Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
title_full Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
title_fullStr Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
title_full_unstemmed Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
title_short Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
title_sort computed tomography imaging features of malignant triton tumor to facilitate its clinical diagnosis report of two cases
topic Computed tomography
Malignant triton tumor
Presumptive diagnosis
Case report
url https://doi.org/10.1186/s12880-022-00848-9
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