Development of a murine model to study the cerebral pathogenesis of Aspergillus fumigatus

Development of a murine model to study the cerebral pathogenesis of Aspergillus fumigatus

ABSTRACTFungal infections of the central nervous system are associated with high mortality and limited treatment options due to the poor permeability of the blood brain barrier to most antifungal drugs. The most common pathogenic mold is Aspergillus fumigatus, which typically causes invasive pulmona...

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Bibliographic Details
Main Authors: Martin T. Kelty, Sarah R. Beattie
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mSphere
Subjects:
fungal infection
central nervous system infections
Aspergillus
Online Access:https://journals.asm.org/doi/10.1128/msphere.00468-23

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