Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults
Probiotics are consumed in a wide variety of fermented foods to improve health. This study was conducted to investigate the effects of Lactobacillus helveticus-fermented milk (LHFM), on cognitive function in healthy older adults. A 12-week, double-blind, randomized controlled experiment was conducte...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
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Elsevier
2014-09-01
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Series: | Journal of Functional Foods |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464614002357 |
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author | Young-Chul Chung Hong-Mei Jin Yin Cui Dal Sik Kim Jin Mu Jung Jong-Il Park Eun-Soo Jung Eun-Kyung Choi Soo-Wan Chae |
author_facet | Young-Chul Chung Hong-Mei Jin Yin Cui Dal Sik Kim Jin Mu Jung Jong-Il Park Eun-Soo Jung Eun-Kyung Choi Soo-Wan Chae |
author_sort | Young-Chul Chung |
collection | DOAJ |
description | Probiotics are consumed in a wide variety of fermented foods to improve health. This study was conducted to investigate the effects of Lactobacillus helveticus-fermented milk (LHFM), on cognitive function in healthy older adults. A 12-week, double-blind, randomized controlled experiment was conducted. Cognitive tests (neuropsychological and cognitive fatigue) and measurements of the perceived stress scale (PSS), geriatric depression scale-short form (GDS-SF), brain-derived neurotrophic factor (BDNF) and whole blood viscosity (WBV) were conducted before and after the experiment. The administration of LHFM for 12 weeks in healthy older adults produced improvement on cognitive tests compared to the placebo group. However, no significant effects were observed for PSS, GDS-SF, BDNF, and WBV. Thus, consumption of LHFM might be beneficial for improving cognitive function. |
first_indexed | 2024-12-14T12:48:35Z |
format | Article |
id | doaj.art-474e901c6ff14ff19892135eba88ea9b |
institution | Directory Open Access Journal |
issn | 1756-4646 |
language | English |
last_indexed | 2024-12-14T12:48:35Z |
publishDate | 2014-09-01 |
publisher | Elsevier |
record_format | Article |
series | Journal of Functional Foods |
spelling | doaj.art-474e901c6ff14ff19892135eba88ea9b2022-12-21T23:00:43ZengElsevierJournal of Functional Foods1756-46462014-09-0110465474Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adultsYoung-Chul Chung0Hong-Mei Jin1Yin Cui2Dal Sik Kim3Jin Mu Jung4Jong-Il Park5Eun-Soo Jung6Eun-Kyung Choi7Soo-Wan Chae8Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea; Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, KoreaDepartment of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea; Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, KoreaDepartment of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea; Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, KoreaResearch Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea; Department of Laboratory Medicine, Chonbuk National University Medical School, Jeonju, KoreaHemorheology Research Institute, Chonbuk National University, Jeonju, KoreaResearch Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, KoreaClinical Trial Center for Functional Foods, Chonbuk National University Hospital, Jeonju, KoreaClinical Trial Center for Functional Foods, Chonbuk National University Hospital, Jeonju, KoreaClinical Trial Center for Functional Foods, Chonbuk National University Hospital, Jeonju, Korea; Department of Pharmacology, Chonbuk National University Medical School, Jeonju, Korea; Corresponding author. Tel.: +82 63 250 2348; fax: +82 63 250 2349.Probiotics are consumed in a wide variety of fermented foods to improve health. This study was conducted to investigate the effects of Lactobacillus helveticus-fermented milk (LHFM), on cognitive function in healthy older adults. A 12-week, double-blind, randomized controlled experiment was conducted. Cognitive tests (neuropsychological and cognitive fatigue) and measurements of the perceived stress scale (PSS), geriatric depression scale-short form (GDS-SF), brain-derived neurotrophic factor (BDNF) and whole blood viscosity (WBV) were conducted before and after the experiment. The administration of LHFM for 12 weeks in healthy older adults produced improvement on cognitive tests compared to the placebo group. However, no significant effects were observed for PSS, GDS-SF, BDNF, and WBV. Thus, consumption of LHFM might be beneficial for improving cognitive function.http://www.sciencedirect.com/science/article/pii/S1756464614002357Lactobacillus helveticusCognitive functionOlder adult |
spellingShingle | Young-Chul Chung Hong-Mei Jin Yin Cui Dal Sik Kim Jin Mu Jung Jong-Il Park Eun-Soo Jung Eun-Kyung Choi Soo-Wan Chae Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults Journal of Functional Foods Lactobacillus helveticus Cognitive function Older adult |
title | Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults |
title_full | Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults |
title_fullStr | Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults |
title_full_unstemmed | Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults |
title_short | Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults |
title_sort | fermented milk of lactobacillus helveticus idcc3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults |
topic | Lactobacillus helveticus Cognitive function Older adult |
url | http://www.sciencedirect.com/science/article/pii/S1756464614002357 |
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