Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults

Probiotics are consumed in a wide variety of fermented foods to improve health. This study was conducted to investigate the effects of Lactobacillus helveticus-fermented milk (LHFM), on cognitive function in healthy older adults. A 12-week, double-blind, randomized controlled experiment was conducte...

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Main Authors: Young-Chul Chung, Hong-Mei Jin, Yin Cui, Dal Sik Kim, Jin Mu Jung, Jong-Il Park, Eun-Soo Jung, Eun-Kyung Choi, Soo-Wan Chae
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464614002357
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author Young-Chul Chung
Hong-Mei Jin
Yin Cui
Dal Sik Kim
Jin Mu Jung
Jong-Il Park
Eun-Soo Jung
Eun-Kyung Choi
Soo-Wan Chae
author_facet Young-Chul Chung
Hong-Mei Jin
Yin Cui
Dal Sik Kim
Jin Mu Jung
Jong-Il Park
Eun-Soo Jung
Eun-Kyung Choi
Soo-Wan Chae
author_sort Young-Chul Chung
collection DOAJ
description Probiotics are consumed in a wide variety of fermented foods to improve health. This study was conducted to investigate the effects of Lactobacillus helveticus-fermented milk (LHFM), on cognitive function in healthy older adults. A 12-week, double-blind, randomized controlled experiment was conducted. Cognitive tests (neuropsychological and cognitive fatigue) and measurements of the perceived stress scale (PSS), geriatric depression scale-short form (GDS-SF), brain-derived neurotrophic factor (BDNF) and whole blood viscosity (WBV) were conducted before and after the experiment. The administration of LHFM for 12 weeks in healthy older adults produced improvement on cognitive tests compared to the placebo group. However, no significant effects were observed for PSS, GDS-SF, BDNF, and WBV. Thus, consumption of LHFM might be beneficial for improving cognitive function.
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spelling doaj.art-474e901c6ff14ff19892135eba88ea9b2022-12-21T23:00:43ZengElsevierJournal of Functional Foods1756-46462014-09-0110465474Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adultsYoung-Chul Chung0Hong-Mei Jin1Yin Cui2Dal Sik Kim3Jin Mu Jung4Jong-Il Park5Eun-Soo Jung6Eun-Kyung Choi7Soo-Wan Chae8Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea; Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, KoreaDepartment of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea; Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, KoreaDepartment of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea; Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, KoreaResearch Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea; Department of Laboratory Medicine, Chonbuk National University Medical School, Jeonju, KoreaHemorheology Research Institute, Chonbuk National University, Jeonju, KoreaResearch Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, KoreaClinical Trial Center for Functional Foods, Chonbuk National University Hospital, Jeonju, KoreaClinical Trial Center for Functional Foods, Chonbuk National University Hospital, Jeonju, KoreaClinical Trial Center for Functional Foods, Chonbuk National University Hospital, Jeonju, Korea; Department of Pharmacology, Chonbuk National University Medical School, Jeonju, Korea; Corresponding author. Tel.: +82 63 250 2348; fax: +82 63 250 2349.Probiotics are consumed in a wide variety of fermented foods to improve health. This study was conducted to investigate the effects of Lactobacillus helveticus-fermented milk (LHFM), on cognitive function in healthy older adults. A 12-week, double-blind, randomized controlled experiment was conducted. Cognitive tests (neuropsychological and cognitive fatigue) and measurements of the perceived stress scale (PSS), geriatric depression scale-short form (GDS-SF), brain-derived neurotrophic factor (BDNF) and whole blood viscosity (WBV) were conducted before and after the experiment. The administration of LHFM for 12 weeks in healthy older adults produced improvement on cognitive tests compared to the placebo group. However, no significant effects were observed for PSS, GDS-SF, BDNF, and WBV. Thus, consumption of LHFM might be beneficial for improving cognitive function.http://www.sciencedirect.com/science/article/pii/S1756464614002357Lactobacillus helveticusCognitive functionOlder adult
spellingShingle Young-Chul Chung
Hong-Mei Jin
Yin Cui
Dal Sik Kim
Jin Mu Jung
Jong-Il Park
Eun-Soo Jung
Eun-Kyung Choi
Soo-Wan Chae
Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults
Journal of Functional Foods
Lactobacillus helveticus
Cognitive function
Older adult
title Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults
title_full Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults
title_fullStr Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults
title_full_unstemmed Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults
title_short Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults
title_sort fermented milk of lactobacillus helveticus idcc3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults
topic Lactobacillus helveticus
Cognitive function
Older adult
url http://www.sciencedirect.com/science/article/pii/S1756464614002357
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