Fatty acid synthase cooperates with glyoxalase 1 to protect against sugar toxicity.
Fatty acid (FA) metabolism is deregulated in several human diseases including metabolic syndrome, type 2 diabetes and cancers. Therefore, FA-metabolic enzymes are potential targets for drug therapy, although the consequence of these treatments must be precisely evaluated at the organismal and cellul...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-02-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC4334898?pdf=render |