Beneficial Effects of Caffeic Acid Phenethyl Ester on Wound Healing in a Diabetic Mouse: Role of VEGF and NO

Beneficial Effects of Caffeic Acid Phenethyl Ester on Wound Healing in a Diabetic Mouse: Role of VEGF and NO

Cutaneous wound healing is delayed in patients with diabetes. Caffeic acid phenethyl ester (CAPE) has been identified as an effective constituent of propolis with improved wound healing abilities via an oxidative stress decrease. However, its impact on wound healing in diabetic models and its underl...

Full description

Bibliographic Details
Main Authors:	Sin-Hee Park, Soo-Young Song, Eun-Hye Park, Eunmin Kim, Gyu Chul Oh, Eun Ho Choo, Byung-Hee Hwang, Kiyuk Chang, Min-Ho Oak
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	Applied Sciences
Subjects:	caffeic acid phenethyl ester wound healing vascular endothelial growth factor nitric oxide
Online Access:	https://www.mdpi.com/2076-3417/12/5/2320

Similar Items

Caffeic Acid Phenethyl Ester Reduces the Adverse Effects of Nicotine on the Endometrium
by: Amin Namdari, et al.
Published: (2023-09-01)

Bone resorption, matrix metalloproteinases and caffeic acid phenethyl ester
by: Sumeyya Akyol, et al.
Published: (2016-12-01)

The Pluripotent Activities of Caffeic Acid Phenethyl Ester
by: Batoryna Olgierd, et al.
Published: (2021-03-01)

Protective Effect of Caffeic Acid Phenethyl Ester in Rat Cerebral Ischemia/Reperfusion Damage
by: Ertuğrul Uzar, et al.
Published: (2011-09-01)

Protective Effect of Caffeic Acid Phenethyl Ester in Rat Cerebral Ischemia/Reperfusion Damage
by: Ertuğrul Uzar, et al.
Published: (2011-09-01)

Promising influences of caffeic acid and caffeic acid phenethyl ester against natural and chemical toxins: A comprehensive and mechanistic review
by: Sajjad Ehtiati, et al.
Published: (2023-08-01)

Caffeic Acid Phenethyl Ester (CAPE) Synergistically Enhances Paclitaxel Activity in Ovarian Cancer Cells
by: Anna Kleczka, et al.
Published: (2023-08-01)

Caffeic Acid Phenethyl Ester Assisted by Reversible Electroporation—In Vitro Study on Human Melanoma Cells
by: Anna Choromanska, et al.
Published: (2020-05-01)

The protective effect of caffeic acid phenethyl ester in the nephrotoxicity induced by α-cypermethrin
by: Nur Gokhan, et al.
Published: (2023-08-01)

The Immunoregulatory Effects of Caffeic Acid Phenethyl Ester on the Cytokine Secretion of Peripheral Blood Mononuclear Cells From Asthmatic Children
by: Leticia Bautista Sy, et al.
Published: (2011-12-01)

Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives
by: Pengxuan Zhang, et al.
Published: (2014-10-01)

Research progress on synthesis and application of caffeic acid phenethyl ester in propolis
by: Meimei ZHANG, et al.
Published: (2020-12-01)

Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity: An experimental study
by: Fuat Aydemir, et al.
Published: (2022-01-01)

Attenuating effects of caffeic acid phenethyl ester with intralipid on hepatotoxicity of chlorpyrifos in the case of rats
by: Recep Dokuyucu, et al.
Published: (2016-12-01)

Caffeic Acid Phenethyl Ester and Ethanol Extract of Propolis Induce the Complementary Cytotoxic Effect on Triple-Negative Breast Cancer Cell Lines
by: Anna Rzepecka-Stojko, et al.
Published: (2015-05-01)

In Vitro Activity of Caffeic Acid Phenethyl Ester against Different Oral Microorganisms
by: Rasha AlSheikh, et al.
Published: (2022-04-01)

Evaluation of antioxidant activity of caffeic acid phenethyl ester loaded block copolymer micelles
by: Krassimira Yoncheva, et al.
Published: (2019-01-01)

Effects of Temperature, Metal Ions and Biosurfactants on Interaction Mechanism between Caffeic Acid Phenethyl Ester and Hemoglobin
by: Yutong Li, et al.
Published: (2023-04-01)

Caffeic Acid Phenethyl Ester With Mesenchymal Stem Cells Improves Behavioral and Histopathological Changes in the Rat Model of Parkinson Disease
by: Khojasteh Rahimi Jaberi, et al.
Published: (2022-09-01)

Caffeic acid phenethyl ester inhibits MDA-MB-231 cell proliferation in inflammatory microenvironment by suppressing glycolysis and lipid metabolism
by: Qian Wu, et al.
Published: (2023-12-01)

Caffeic acid phenethyl ester attenuates neuropathic pain by suppressing the p38/NF-κB signal pathway in microglia
by: Cheng H, et al.
Published: (2018-11-01)

Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213
by: Ying-Yu Kuo, et al.
Published: (2019-08-01)

The impact of caffeic acid phenethyl ester, chrysin and ethanolic extracts of propolis on PLD1 gene expression in AGS cell line
by: Hamideh Jafari-Ghahfarokhi, et al.
Published: (2019-10-01)

Redox-Responsive Crosslinked Mixed Micelles for Controllable Release of Caffeic Acid Phenethyl Ester
by: Katya Kamenova, et al.
Published: (2022-03-01)

Caffeic Acid Phenethyl Ester (CAPE): Biosynthesis, Derivatives and Formulations with Neuroprotective Activities
by: Rebeca Pérez, et al.
Published: (2023-07-01)

IL-8 as a Potential Therapeutic Target for Periodontitis and Its Inhibition by Caffeic Acid Phenethyl Ester In Vitro
by: Yung-Kai Huang, et al.
Published: (2021-03-01)

Regulatory Effect of Caffeic Acid Phenethyl Ester on Oxidative Stress and Lipid Metabolism in HepG2 Cells
by: LIU Chang, CHANG Chao, CHEN Ruida, LIN Menghui, SUN Rong, CAI Chenggang, ZHAO Minjie, CAI Haiying
Published: (2023-09-01)

Caffeic Acid Phenethyl Ester Protects Kidney Mitochondria against Ischemia/Reperfusion Induced Injury in an <i>In Vivo</i> Rat Model
by: Justina Kamarauskaite, et al.
Published: (2021-05-01)

Caffeic Acid Phenethyl Ester (CAPE) Induced Apoptosis in Serous Ovarian Cancer OV7 Cells by Deregulation of BCL2/BAX Genes
by: Anna Kleczka, et al.
Published: (2020-07-01)

Caffeic Acid Phenethyl Ester (CAPE) Inhibits Cross-Kingdom Biofilm Formation of Streptococcus mutans and Candida albicans
by: Wumeng Yin, et al.
Published: (2022-10-01)

Ameliorating Role of Caffeic Acid Phenethyl Ester (CAPE) Against Methotrexate-Induced Oxidative Stress in the Sciatic Nerve, Spinal Cord and Brain Stem Tissues of Rats
by: Ertuğrul Uzar, et al.
Published: (2010-03-01)

Ameliorating Role of Caffeic Acid Phenethyl Ester (CAPE) Against Methotrexate-Induced Oxidative Stress in the Sciatic Nerve, Spinal Cord and Brain Stem Tissues of Rats
by: Ertuğrul Uzar, et al.
Published: (2010-03-01)

The Anti-Biofilm Efficacy of Caffeic Acid Phenethyl Ester (CAPE) In Vitro and a Murine Model of Oral Candidiasis
by: Patrícia Pimentel de Barros, et al.
Published: (2021-08-01)

Cooperative Reinforcement of Ionic Liquid and Reactive Solvent on Enzymatic Synthesis of Caffeic Acid Phenethyl Ester as an In Vitro Inhibitor of Plant Pathogenic Bacteria
by: Yan Xu, et al.
Published: (2017-01-01)

Caffeic Acid Phenethyl Ester Prevents Colitis-Associated Cancer by Inhibiting NLRP3 Inflammasome
by: Guoliang Dai, et al.
Published: (2020-05-01)

Combination treatment of docetaxel with caffeic acid phenethyl ester suppresses the survival and the proliferation of docetaxel-resistant prostate cancer cells via induction of apoptosis and metabolism interference
by: Yu-Ke Fu, et al.
Published: (2022-02-01)

Caffeic acid phenethyl ester mitigates cadmium-induced hepatotoxicity in mice: Role of miR-182-5p/TLR4 axis
by: Rili Hao, et al.
Published: (2021-01-01)

Caffeic Acid Phenethyl Ester and Caffeamide Derivatives Suppress Oral Squamous Cell Carcinoma Cells
by: Yin-Hwa Shih, et al.
Published: (2023-06-01)

A Nano-Liposomal Formulation of Caffeic Acid Phenethyl Ester Modulates Nrf2 and NF-κβ Signaling and Alleviates Experimentally Induced Acute Pancreatitis in a Rat Model
by: Nancy Nabil Shahin, et al.
Published: (2022-08-01)

Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers
by: Vidhi Malik, et al.
Published: (2021-01-01)