Evaluation of Plasma Asprosin Concentration in Patients with Coronary Artery Disease

Abstract Introduction: The goal of this study is to investigate the association between diagnosis and severity of coronary artery disease (CAD) and Asprosin level. Methods: Patients diagnosed with CAD who underwent conventional coronary angiography for the first time were included in the present s...

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Main Authors: Cengiz Güven, Hüseyin Kafadar
Format: Article
Language:English
Published: Sociedade Brasileira de Cirurgia Cardiovascular 2022-01-01
Series:Brazilian Journal of Cardiovascular Surgery
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382022005001212&tlng=en
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author Cengiz Güven
Hüseyin Kafadar
author_facet Cengiz Güven
Hüseyin Kafadar
author_sort Cengiz Güven
collection DOAJ
description Abstract Introduction: The goal of this study is to investigate the association between diagnosis and severity of coronary artery disease (CAD) and Asprosin level. Methods: Patients diagnosed with CAD who underwent conventional coronary angiography for the first time were included in the present study. The patients were divided into four groups, each consisting of 20 individuals, as medical group, single coronary lesion group, double coronary lesion group, and multiple coronary lesions group. Serum Asprosin values and Gensini scores of the groups were compared in terms of compliance. Results: In this study, Asprosin values were found to be significantly higher in the multiple coronary lesions group than in the medical, single coronary, and double coronary lesion groups (P<0.05). In the double coronary lesion group, Asprosin values were significantly higher (P<0.05) than the in the medical and single coronary lesion groups. It was also found that Asprosin values did not differ at significant levels in the medical and single coronary lesion groups (P>0.05). It was determined that the increases in Asprosin values and Gensini scores were compatible with each other. Conclusion: The present study showed that the increases in serum Asprosin levels, along with the increases in the number of coronary arteries with critical stenosis, might be a marker in diagnosing and determining the severity of CAD.
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spelling doaj.art-476c043259d84a91927083200f8b8a3a2022-12-22T03:25:41ZengSociedade Brasileira de Cirurgia CardiovascularBrazilian Journal of Cardiovascular Surgery1678-97412022-01-0110.21470/1678-9741-2021-0003Evaluation of Plasma Asprosin Concentration in Patients with Coronary Artery DiseaseCengiz Güvenhttps://orcid.org/0000-0001-9693-434XHüseyin KafadarAbstract Introduction: The goal of this study is to investigate the association between diagnosis and severity of coronary artery disease (CAD) and Asprosin level. Methods: Patients diagnosed with CAD who underwent conventional coronary angiography for the first time were included in the present study. The patients were divided into four groups, each consisting of 20 individuals, as medical group, single coronary lesion group, double coronary lesion group, and multiple coronary lesions group. Serum Asprosin values and Gensini scores of the groups were compared in terms of compliance. Results: In this study, Asprosin values were found to be significantly higher in the multiple coronary lesions group than in the medical, single coronary, and double coronary lesion groups (P<0.05). In the double coronary lesion group, Asprosin values were significantly higher (P<0.05) than the in the medical and single coronary lesion groups. It was also found that Asprosin values did not differ at significant levels in the medical and single coronary lesion groups (P>0.05). It was determined that the increases in Asprosin values and Gensini scores were compatible with each other. Conclusion: The present study showed that the increases in serum Asprosin levels, along with the increases in the number of coronary arteries with critical stenosis, might be a marker in diagnosing and determining the severity of CAD.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382022005001212&tlng=enAsprosinCoronary Artery DiseaseCoronary AngiographySeverity of Illness IndexRisk Factors
spellingShingle Cengiz Güven
Hüseyin Kafadar
Evaluation of Plasma Asprosin Concentration in Patients with Coronary Artery Disease
Brazilian Journal of Cardiovascular Surgery
Asprosin
Coronary Artery Disease
Coronary Angiography
Severity of Illness Index
Risk Factors
title Evaluation of Plasma Asprosin Concentration in Patients with Coronary Artery Disease
title_full Evaluation of Plasma Asprosin Concentration in Patients with Coronary Artery Disease
title_fullStr Evaluation of Plasma Asprosin Concentration in Patients with Coronary Artery Disease
title_full_unstemmed Evaluation of Plasma Asprosin Concentration in Patients with Coronary Artery Disease
title_short Evaluation of Plasma Asprosin Concentration in Patients with Coronary Artery Disease
title_sort evaluation of plasma asprosin concentration in patients with coronary artery disease
topic Asprosin
Coronary Artery Disease
Coronary Angiography
Severity of Illness Index
Risk Factors
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382022005001212&tlng=en
work_keys_str_mv AT cengizguven evaluationofplasmaasprosinconcentrationinpatientswithcoronaryarterydisease
AT huseyinkafadar evaluationofplasmaasprosinconcentrationinpatientswithcoronaryarterydisease