Early fecal microbiota transplantation from high abdominal fat chickens affects recipient cecal microbiome and metabolism
Abdominal fat deposition (AFD) in chickens is closely related to the gut microecological balance. In this study, the gut microbiota from high-AFD chickens was transplanted into the same strain of 0-day-old chicks via fecal microbiota transplantation (FMT). The FTM from chickens with high AFD had no...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1332230/full |
| _version_ | 1797362307559325696 |
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| author | Jiani Song Chaowei Luo Zhijie Liu Jingshou Liu Li Xie Xing Zhang Zhuojun Xie Xiangkun Li Zheng Ma Jinlong Ding Hua Li Hua Li Hai Xiang |
| author_facet | Jiani Song Chaowei Luo Zhijie Liu Jingshou Liu Li Xie Xing Zhang Zhuojun Xie Xiangkun Li Zheng Ma Jinlong Ding Hua Li Hua Li Hai Xiang |
| author_sort | Jiani Song |
| collection | DOAJ |
| description | Abdominal fat deposition (AFD) in chickens is closely related to the gut microecological balance. In this study, the gut microbiota from high-AFD chickens was transplanted into the same strain of 0-day-old chicks via fecal microbiota transplantation (FMT). The FTM from chickens with high AFD had no obvious effects on growth traits, adult body weight, carcass weight, abdominal fat weight, and abdominal fat percentage, but did reduce the coefficient of variation of AFD traits. FMT significantly decreased cecal microbiome richness, changed the microbiota structure, and regulated the biological functions associated with energy metabolism and fat synthesis. Additionally, the cecal metabolite composition and metabolic function of FMT recipient chickens were also significantly altered from those of the controls. Transplantation of high-AFD chicken gut microbiota promoted fatty acid elongation and biosynthesis and reduced the metabolism of vitamins, steroids, and carbohydrates in the cecum. These findings provide insights into the mechanisms by which chicken gut microbiota affect host metabolic profiles and fat deposition. |
| first_indexed | 2024-03-08T16:06:19Z |
| format | Article |
| id | doaj.art-476dfb310e404523a5dc188a1f5ec6bc |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-03-08T16:06:19Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-476dfb310e404523a5dc188a1f5ec6bc2024-01-08T05:45:13ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2024-01-011410.3389/fmicb.2023.13322301332230Early fecal microbiota transplantation from high abdominal fat chickens affects recipient cecal microbiome and metabolismJiani Song0Chaowei Luo1Zhijie Liu2Jingshou Liu3Li Xie4Xing Zhang5Zhuojun Xie6Xiangkun Li7Zheng Ma8Jinlong Ding9Hua Li10Hua Li11Hai Xiang12Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, ChinaGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, ChinaGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, ChinaGuangdong Tinoo’s Foods Group Co., Ltd., Guangdong, ChinaGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, ChinaGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, ChinaGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, ChinaGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, ChinaGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, ChinaGuangdong Tinoo’s Foods Group Co., Ltd., Guangdong, ChinaGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, ChinaGuangdong Tinoo’s Foods Group Co., Ltd., Guangdong, ChinaGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Life Science and Engineering, Foshan University, Foshan, ChinaAbdominal fat deposition (AFD) in chickens is closely related to the gut microecological balance. In this study, the gut microbiota from high-AFD chickens was transplanted into the same strain of 0-day-old chicks via fecal microbiota transplantation (FMT). The FTM from chickens with high AFD had no obvious effects on growth traits, adult body weight, carcass weight, abdominal fat weight, and abdominal fat percentage, but did reduce the coefficient of variation of AFD traits. FMT significantly decreased cecal microbiome richness, changed the microbiota structure, and regulated the biological functions associated with energy metabolism and fat synthesis. Additionally, the cecal metabolite composition and metabolic function of FMT recipient chickens were also significantly altered from those of the controls. Transplantation of high-AFD chicken gut microbiota promoted fatty acid elongation and biosynthesis and reduced the metabolism of vitamins, steroids, and carbohydrates in the cecum. These findings provide insights into the mechanisms by which chicken gut microbiota affect host metabolic profiles and fat deposition.https://www.frontiersin.org/articles/10.3389/fmicb.2023.1332230/fullgut microbiotacecal microbiomechickensfecal microbiota transplantationfatty acids |
| spellingShingle | Jiani Song Chaowei Luo Zhijie Liu Jingshou Liu Li Xie Xing Zhang Zhuojun Xie Xiangkun Li Zheng Ma Jinlong Ding Hua Li Hua Li Hai Xiang Early fecal microbiota transplantation from high abdominal fat chickens affects recipient cecal microbiome and metabolism Frontiers in Microbiology gut microbiota cecal microbiome chickens fecal microbiota transplantation fatty acids |
| title | Early fecal microbiota transplantation from high abdominal fat chickens affects recipient cecal microbiome and metabolism |
| title_full | Early fecal microbiota transplantation from high abdominal fat chickens affects recipient cecal microbiome and metabolism |
| title_fullStr | Early fecal microbiota transplantation from high abdominal fat chickens affects recipient cecal microbiome and metabolism |
| title_full_unstemmed | Early fecal microbiota transplantation from high abdominal fat chickens affects recipient cecal microbiome and metabolism |
| title_short | Early fecal microbiota transplantation from high abdominal fat chickens affects recipient cecal microbiome and metabolism |
| title_sort | early fecal microbiota transplantation from high abdominal fat chickens affects recipient cecal microbiome and metabolism |
| topic | gut microbiota cecal microbiome chickens fecal microbiota transplantation fatty acids |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1332230/full |
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