A review of synthetic methods of 1,2,4-triazolopyridines and their therapeutic properties

This review summarizes data on the synthesis of important aromatic core [1,2,4]triazolopyridines. The presented methods are classified according to the types of reagents used. Therefore, the variety of reagents used in the classification of different synthesis methods of triazolopyridines is effecti...

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Main Authors: S. Poormoradkhan Melal, N.O. Mahmoodi
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623000218
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author S. Poormoradkhan Melal
N.O. Mahmoodi
author_facet S. Poormoradkhan Melal
N.O. Mahmoodi
author_sort S. Poormoradkhan Melal
collection DOAJ
description This review summarizes data on the synthesis of important aromatic core [1,2,4]triazolopyridines. The presented methods are classified according to the types of reagents used. Therefore, the variety of reagents used in the classification of different synthesis methods of triazolopyridines is effective. [1,2,4]Triazolopyridines are an important class of heterocyclic compounds that have a wide range of pharmaceutical and biological activities including herbicidal, antifungal, anticonvulsant, and anxiolytic activities. Although several methods for the synthesis of [1,2,4]triazolopyridines have been reported in the literature, many of them require rigid reaction conditions or are multistep in nature, and there is still a need for further novel research methods in the future.
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spelling doaj.art-47740a1240a34d7d9462313b18f19a622023-06-21T06:52:00ZengElsevierResults in Chemistry2211-71562023-01-015100782A review of synthetic methods of 1,2,4-triazolopyridines and their therapeutic propertiesS. Poormoradkhan Melal0N.O. Mahmoodi1Department of Organic Chemistry, Faculty of Science, University of Guilan, Rasht, IranCorresponding author.; Department of Organic Chemistry, Faculty of Science, University of Guilan, Rasht, IranThis review summarizes data on the synthesis of important aromatic core [1,2,4]triazolopyridines. The presented methods are classified according to the types of reagents used. Therefore, the variety of reagents used in the classification of different synthesis methods of triazolopyridines is effective. [1,2,4]Triazolopyridines are an important class of heterocyclic compounds that have a wide range of pharmaceutical and biological activities including herbicidal, antifungal, anticonvulsant, and anxiolytic activities. Although several methods for the synthesis of [1,2,4]triazolopyridines have been reported in the literature, many of them require rigid reaction conditions or are multistep in nature, and there is still a need for further novel research methods in the future.http://www.sciencedirect.com/science/article/pii/S22117156230002181,2, 4-TriazolopyridineHydrazinopyridinePoly (hetero) aromaticOxidation Molecular Cyclization
spellingShingle S. Poormoradkhan Melal
N.O. Mahmoodi
A review of synthetic methods of 1,2,4-triazolopyridines and their therapeutic properties
Results in Chemistry
1,2, 4-Triazolopyridine
Hydrazinopyridine
Poly (hetero) aromatic
Oxidation Molecular Cyclization
title A review of synthetic methods of 1,2,4-triazolopyridines and their therapeutic properties
title_full A review of synthetic methods of 1,2,4-triazolopyridines and their therapeutic properties
title_fullStr A review of synthetic methods of 1,2,4-triazolopyridines and their therapeutic properties
title_full_unstemmed A review of synthetic methods of 1,2,4-triazolopyridines and their therapeutic properties
title_short A review of synthetic methods of 1,2,4-triazolopyridines and their therapeutic properties
title_sort review of synthetic methods of 1 2 4 triazolopyridines and their therapeutic properties
topic 1,2, 4-Triazolopyridine
Hydrazinopyridine
Poly (hetero) aromatic
Oxidation Molecular Cyclization
url http://www.sciencedirect.com/science/article/pii/S2211715623000218
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