Evaluation of the In Vitro and In Vivo Efficacy of Ruthenium Polypyridyl Compounds against Breast Cancer

Evaluation of the In Vitro and In Vivo Efficacy of Ruthenium Polypyridyl Compounds against Breast Cancer

The clinical success of cisplatin, carboplatin, and oxaliplatin has sparked the interest of medicinal inorganic chemistry to synthesize and study compounds with non-platinum metal centers. Despite Ru(II)–polypyridyl complexes being widely studied and well established for their antitumor properties,...

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Bibliographic Details
Main Authors: Oscar A. Lenis-Rojas, Catarina Roma-Rodrigues, Alexandra R. Fernandes, Andreia Carvalho, Sandra Cordeiro, Jorge Guerra-Varela, Laura Sánchez, Digna Vázquez-García, Margarita López-Torres, Alberto Fernández, Jesús J. Fernández
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
ruthenium
polypyridyl compounds
cytotoxicity
cell death
cell cycle
in vivo toxicity
Online Access:https://www.mdpi.com/1422-0067/22/16/8916

Internet

https://www.mdpi.com/1422-0067/22/16/8916

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