A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia

Background: Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor, and MECs of the lung are rare, accounting for 0.1–0.2% of malignant lung tumors. Pulmonary MECs are commonly found in the segmental or lobar bronchi, rarely presenting as endobronchial lesions. Case present...

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Main Authors: Toolsie Omesh, Ranjan Gupta, Anjali Saqi, Joshua Burack, Misbahuddin Khaja
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Respiratory Medicine Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007118302144
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author Toolsie Omesh
Ranjan Gupta
Anjali Saqi
Joshua Burack
Misbahuddin Khaja
author_facet Toolsie Omesh
Ranjan Gupta
Anjali Saqi
Joshua Burack
Misbahuddin Khaja
author_sort Toolsie Omesh
collection DOAJ
description Background: Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor, and MECs of the lung are rare, accounting for 0.1–0.2% of malignant lung tumors. Pulmonary MECs are commonly found in the segmental or lobar bronchi, rarely presenting as endobronchial lesions. Case presentation: Here we describe the case of a 21-year-old female with no comorbid conditions who presented at the emergency room with a cough, yellow phlegm, pleuritic chest pain, and a subjective fever. These symptoms had been present for approximately one week prior to the patient's arrival at the hospital. A chest X-ray revealed right lower lobe alveolar infiltrate and computed tomography of the chest showed dense consolidation of the right lower lobe with ovoid intraluminal density in the right main stem bronchus. Upon fiber optic bronchoscopy, an endobronchial lesion was found in the right main stem sparing the right upper lobe uptake. Endobronchial biopsy results was consistent with MEC of the lung. The patient underwent a bilobectomy with complete resection of the tumor. Conclusion: Endobronchial MEC is a rare type of salivary gland tumor. Patients with low-grade MECs have a good prognosis, whereas those with high-grade MECs, which are aggressive and associated with metastatic disease, have a poor prognosis. However, early identification and surgical resection can result in a good prognosis. Keywords: Mucoepidermoid carcinoma, Endobronchial lesion
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spelling doaj.art-4778efaa6c994cf8b880f8bddf878b5e2022-12-22T01:54:36ZengElsevierRespiratory Medicine Case Reports2213-00712018-01-0125154157A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumoniaToolsie Omesh0Ranjan Gupta1Anjali Saqi2Joshua Burack3Misbahuddin Khaja4Division of Pulmonary and Critical Care Medicine, Bronx Care Health System, Affiliated with Icahn School of Medicine at Mount Sinai, 1650 Grand Concourse, Bronx, NY, 10457, USADepartment of Surgery, Bronx Care Health System, Affiliated with Icahn School of Medicine at Mount Sinai, 1650 Grand Concourse, Bronx, NY, 10457, USADepartment of Pathology, Columbia University Medical Center, USADepartment of Surgery, Bronx Care Health System, Affiliated with Icahn School of Medicine at Mount Sinai, 1650 Grand Concourse, Bronx, NY, 10457, USADivision of Pulmonary and Critical Care Medicine, Bronx Care Health System, Affiliated with Icahn School of Medicine at Mount Sinai, 1650 Grand Concourse, Bronx, NY, 10457, USA; Corresponding author.Background: Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor, and MECs of the lung are rare, accounting for 0.1–0.2% of malignant lung tumors. Pulmonary MECs are commonly found in the segmental or lobar bronchi, rarely presenting as endobronchial lesions. Case presentation: Here we describe the case of a 21-year-old female with no comorbid conditions who presented at the emergency room with a cough, yellow phlegm, pleuritic chest pain, and a subjective fever. These symptoms had been present for approximately one week prior to the patient's arrival at the hospital. A chest X-ray revealed right lower lobe alveolar infiltrate and computed tomography of the chest showed dense consolidation of the right lower lobe with ovoid intraluminal density in the right main stem bronchus. Upon fiber optic bronchoscopy, an endobronchial lesion was found in the right main stem sparing the right upper lobe uptake. Endobronchial biopsy results was consistent with MEC of the lung. The patient underwent a bilobectomy with complete resection of the tumor. Conclusion: Endobronchial MEC is a rare type of salivary gland tumor. Patients with low-grade MECs have a good prognosis, whereas those with high-grade MECs, which are aggressive and associated with metastatic disease, have a poor prognosis. However, early identification and surgical resection can result in a good prognosis. Keywords: Mucoepidermoid carcinoma, Endobronchial lesionhttp://www.sciencedirect.com/science/article/pii/S2213007118302144
spellingShingle Toolsie Omesh
Ranjan Gupta
Anjali Saqi
Joshua Burack
Misbahuddin Khaja
A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
Respiratory Medicine Case Reports
title A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
title_full A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
title_fullStr A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
title_full_unstemmed A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
title_short A rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non-resolving pneumonia
title_sort rare case of endobronchial mucoepidermoid carcinoma of the lung presenting as non resolving pneumonia
url http://www.sciencedirect.com/science/article/pii/S2213007118302144
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