Solitary Fibrous Tumour of the Kidney: Case Report with Review of the Literature
Solitary Fibrous Tumour (SFT) is an unusual spindle cell tumour that usually occurs in the pleura, but has recently also been reported to be extra-pleural in origin. A renal presentation is very rare. Upto 90% of the tumours have benign characteristics. It is difficult to differentiate it from ren...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2013-12-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/3811/92-%207074_E(C)_F(T)_PF1(VP)_PF1(MH)_PFA(H)_PF2(PP)_PF3(PR).pdf |
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| author | Sulata Manjunath Kamath HK Nagaraj Vijaya V Mysorekar Geeta V Patil Mangala Gowri |
| author_facet | Sulata Manjunath Kamath HK Nagaraj Vijaya V Mysorekar Geeta V Patil Mangala Gowri |
| author_sort | Sulata Manjunath Kamath |
| collection | DOAJ |
| description | Solitary Fibrous Tumour (SFT) is an unusual spindle cell tumour that usually occurs in the pleura, but has recently also been reported to be
extra-pleural in origin. A renal presentation is very rare. Upto 90% of the tumours have benign characteristics. It is difficult to differentiate it
from renal cell carcinoma by using imaging techniques. A definitive diagnosis can be made by doing a detailed pathological examination,
which includes immunohistochemistry. We are reporting a case of a large solitary fibrous tumour of the kidney which here occurred in a 70-
years-old male. Histological examination of the resected specimen confirmed the diagnosis, by revealing strongly positive reactions of the
neoplastic cells for CD34, bcl-2, vimentin and negativity for Epithelial Membrane Antigen (EMA), Smooth Muscle Actin (SMA), S-100 protein
and Ki-67. The patient suffered a cardiac arrest and died on the seventh day after his surgery. |
| first_indexed | 2024-12-11T13:33:33Z |
| format | Article |
| id | doaj.art-47794305615e498dbf8ec510605ff921 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-11T13:33:33Z |
| publishDate | 2013-12-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-47794305615e498dbf8ec510605ff9212022-12-22T01:05:09ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2013-12-017122968296910.7860/JCDR/2013/7074.3811Solitary Fibrous Tumour of the Kidney: Case Report with Review of the LiteratureSulata Manjunath Kamath0HK Nagaraj1Vijaya V Mysorekar2Geeta V Patil3Mangala Gowri4Professor, Department of Pathology, M S Ramaiah Medical College & Teaching Hospital, India.Senior Professor, Department of Urology, M S Ramaiah Medical College & Teaching Hospital, India.Senior Professor, Department of Pathology, M S Ramaiah Medical College & Teaching Hospital, India.Assistant Professor, Department of Pathology, M S Ramaiah Medical College & Teaching Hospital, India.Professor, Department of Pathology, M S Ramaiah Medical College & Teaching Hospital, India.Solitary Fibrous Tumour (SFT) is an unusual spindle cell tumour that usually occurs in the pleura, but has recently also been reported to be extra-pleural in origin. A renal presentation is very rare. Upto 90% of the tumours have benign characteristics. It is difficult to differentiate it from renal cell carcinoma by using imaging techniques. A definitive diagnosis can be made by doing a detailed pathological examination, which includes immunohistochemistry. We are reporting a case of a large solitary fibrous tumour of the kidney which here occurred in a 70- years-old male. Histological examination of the resected specimen confirmed the diagnosis, by revealing strongly positive reactions of the neoplastic cells for CD34, bcl-2, vimentin and negativity for Epithelial Membrane Antigen (EMA), Smooth Muscle Actin (SMA), S-100 protein and Ki-67. The patient suffered a cardiac arrest and died on the seventh day after his surgery.https://jcdr.net/articles/PDF/3811/92-%207074_E(C)_F(T)_PF1(VP)_PF1(MH)_PFA(H)_PF2(PP)_PF3(PR).pdfextra-pleuralimmuno-histochemistry |
| spellingShingle | Sulata Manjunath Kamath HK Nagaraj Vijaya V Mysorekar Geeta V Patil Mangala Gowri Solitary Fibrous Tumour of the Kidney: Case Report with Review of the Literature Journal of Clinical and Diagnostic Research extra-pleural immuno-histochemistry |
| title | Solitary Fibrous Tumour of the Kidney: Case Report with Review of the Literature |
| title_full | Solitary Fibrous Tumour of the Kidney: Case Report with Review of the Literature |
| title_fullStr | Solitary Fibrous Tumour of the Kidney: Case Report with Review of the Literature |
| title_full_unstemmed | Solitary Fibrous Tumour of the Kidney: Case Report with Review of the Literature |
| title_short | Solitary Fibrous Tumour of the Kidney: Case Report with Review of the Literature |
| title_sort | solitary fibrous tumour of the kidney case report with review of the literature |
| topic | extra-pleural immuno-histochemistry |
| url | https://jcdr.net/articles/PDF/3811/92-%207074_E(C)_F(T)_PF1(VP)_PF1(MH)_PFA(H)_PF2(PP)_PF3(PR).pdf |
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