Nano-scale architecture of blood-brain barrier tight-junctions

Nano-scale architecture of blood-brain barrier tight-junctions

Tight junctions (TJs) between blood-brain barrier (BBB) endothelial cells construct a robust physical barrier, whose damage underlies BBB dysfunctions related to several neurodegenerative diseases. What makes these highly specialized BBB-TJs extremely restrictive remains unknown. Here, we use super-...

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Bibliographic Details
Main Authors: Esther Sasson, Shira Anzi, Batia Bell, Oren Yakovian, Meshi Zorsky, Urban Deutsch, Britta Engelhardt, Eilon Sherman, Gad Vatine, Ron Dzikowski, Ayal Ben-Zvi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-12-01
Series:eLife
Subjects:
blood-brain-barrier
tight-junction
super-resolution
endothelium
Online Access:https://elifesciences.org/articles/63253

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