The Cif proteins from Wolbachia prophage WO modify sperm genome integrity to establish cytoplasmic incompatibility.

Inherited microorganisms can selfishly manipulate host reproduction to drive through populations. In Drosophila melanogaster, germline expression of the native Wolbachia prophage WO proteins CifA and CifB cause cytoplasmic incompatibility (CI) in which embryos from infected males and uninfected fema...

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Bibliographic Details
Main Authors: Rupinder Kaur, Brittany A Leigh, Isabella T Ritchie, Seth R Bordenstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001584