DENV-2 NS1 promotes AMPK-LKB1 interaction to activate AMPK/ERK/mTOR signaling pathway to induce autophagy

DENV-2 NS1 promotes AMPK-LKB1 interaction to activate AMPK/ERK/mTOR signaling pathway to induce autophagy

Abstract The global incidence of dengue fever has gradually increased in recent years, posing a serious threat to human health. In the absence of specific anti-dengue drugs, understanding the interaction of Dengue virus (DENV) with the host is essential for the development of effective therapeutic m...

Full description

Bibliographic Details
Main Authors: Ning Wu, Jinzhong Ji, Xiaoqin Gou, Pan Hu, Yao Cheng, Yuhang Liu, Yuanying Wang, Qilong Zhang, Li Zuo
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Virology Journal
Subjects:
DENV-2
Autophagy
DENV-2 NS1
AMPK
LKB1
AMPK/ERK/mTOR signaling pathway
Online Access:https://doi.org/10.1186/s12985-023-02166-0

Similar Items

Similar Items