Clostridium Perfringens Enterotoxin (CPE) and CPE-Binding Domain (c-CPE) for the Detection and Treatment of Gynecologic Cancers

Clostridium Perfringens Enterotoxin (CPE) and CPE-Binding Domain (c-CPE) for the Detection and Treatment of Gynecologic Cancers

Clostridium perfringens enterotoxin (CPE) is a three-domain polypeptide, which binds to Claudin-3 and Claudin-4 with high affinity. Because these receptors are highly differentially expressed in many human tumors, claudin-3 and claudin-4 may provide an efficient molecular tool to specifically identi...

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Bibliographic Details
Main Authors: Jonathan D. Black, Salvatore Lopez, Emiliano Cocco, Carlton L. Schwab, Diana P. English, Alessandro D. Santin
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Toxins
Subjects:
clostridium perfringens enterotoxin
gynecologic cancer
Claudin
therapeutics
diagnostics
Online Access:http://www.mdpi.com/2072-6651/7/4/1116

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