Treatment for small-cell lung cancer
Small-cell lung cancer (SCLC) accounts for 13-20% of all lung cancers. Stongly associated with smoking and initially responsive to treatment, it results in death within 2-4 months without treatment. Limited-stage disease is treated with curative intent with chemotherapy and radiation ther...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2008-10-01
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| Series: | Annals of Thoracic Medicine |
| Subjects: | |
| Online Access: | http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2008;volume=3;issue=6;spage=100;epage=103;aulast=Saadeen |
| _version_ | 1811262533625970688 |
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| author | Saadeen Ahmed Jazieh Abdul-Rahman |
| author_facet | Saadeen Ahmed Jazieh Abdul-Rahman |
| author_sort | Saadeen Ahmed |
| collection | DOAJ |
| description | Small-cell lung cancer (SCLC) accounts for 13-20% of all lung cancers. Stongly associated with smoking and initially responsive to treatment, it results in death within 2-4 months without treatment. Limited-stage disease is treated with curative intent with chemotherapy and radiation therapy, with approximately 20% of patients achieving a cure. Extensive-stage disease is primarily treated with chemotherapy and has a high initial response rate of 60-70% but the median survival is only 10 months. All patients achieving a complete remission should be offered prophylactic cranial irradiation. Relapsed or refractory SCLC has a uniformly poor prognosis. |
| first_indexed | 2024-04-12T19:27:19Z |
| format | Article |
| id | doaj.art-47804156d6df46cd8eaad6abe27e2880 |
| institution | Directory Open Access Journal |
| issn | 1817-1737 1998-3557 |
| language | English |
| last_indexed | 2024-04-12T19:27:19Z |
| publishDate | 2008-10-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Thoracic Medicine |
| spelling | doaj.art-47804156d6df46cd8eaad6abe27e28802022-12-22T03:19:26ZengWolters Kluwer Medknow PublicationsAnnals of Thoracic Medicine1817-17371998-35572008-10-0136100103Treatment for small-cell lung cancerSaadeen AhmedJazieh Abdul-RahmanSmall-cell lung cancer (SCLC) accounts for 13-20% of all lung cancers. Stongly associated with smoking and initially responsive to treatment, it results in death within 2-4 months without treatment. Limited-stage disease is treated with curative intent with chemotherapy and radiation therapy, with approximately 20% of patients achieving a cure. Extensive-stage disease is primarily treated with chemotherapy and has a high initial response rate of 60-70% but the median survival is only 10 months. All patients achieving a complete remission should be offered prophylactic cranial irradiation. Relapsed or refractory SCLC has a uniformly poor prognosis.http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2008;volume=3;issue=6;spage=100;epage=103;aulast=SaadeenSmall cell lung cancertreatmentradiationchemotherapy |
| spellingShingle | Saadeen Ahmed Jazieh Abdul-Rahman Treatment for small-cell lung cancer Annals of Thoracic Medicine Small cell lung cancer treatment radiation chemotherapy |
| title | Treatment for small-cell lung cancer |
| title_full | Treatment for small-cell lung cancer |
| title_fullStr | Treatment for small-cell lung cancer |
| title_full_unstemmed | Treatment for small-cell lung cancer |
| title_short | Treatment for small-cell lung cancer |
| title_sort | treatment for small cell lung cancer |
| topic | Small cell lung cancer treatment radiation chemotherapy |
| url | http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2008;volume=3;issue=6;spage=100;epage=103;aulast=Saadeen |
| work_keys_str_mv | AT saadeenahmed treatmentforsmallcelllungcancer AT jaziehabdulrahman treatmentforsmallcelllungcancer |