M6A-mediated upregulation of HOXC10 promotes human hepatocellular carcinoma development through PTEN/AKT/mTOR signaling pathway

M6A-mediated upregulation of HOXC10 promotes human hepatocellular carcinoma development through PTEN/AKT/mTOR signaling pathway

Abstract Human Hox genes (Homeobox) play a crucial role in embryonic development and cancer. The HOXC10 gene, a member of the HOX family, has been reported abnormally expressed in several cancers. However, the association between HOXC10 and hepatocellular carcinoma (HCC) remains to be elucidated. In...

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Bibliographic Details
Main Authors: Miao Li, Qianwen Guo, Qian Shi, Yanzhi Rao, Yixin Dong, Fangjie Chen, Xun Qi
Format: Article
Language:English
Published: Springer 2023-09-01
Series:Discover Oncology
Subjects:
HOXC10 HCC proliferation M6A PTEN
AKT
mTOR pathway
Online Access:https://doi.org/10.1007/s12672-023-00786-0

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