Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis

Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis

Abstract Circular RNAs (circRNAs) are increasingly gaining importance and attention due to their diverse potential functions and their value as diagnostic biomarkers (disease specific). This study aims to explore the novel mechanisms by which exosome-contained circRNAs promote tumor development and...

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Bibliographic Details
Main Authors: Su-jin Yang, Dan-dan Wang, Shan-liang Zhong, Wen-quan Chen, Feng-liang Wang, Jian Zhang, Wen-xiu Xu, Di Xu, Qian Zhang, Jian Li, He-da Zhang, Jun-chen Hou, Ling Mao, Jin-hai Tang
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03680-1

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