The mechanisms of colorectal cancer cell mesenchymal-epithelial transition induced by hepatocyte exosome-derived miR-203a-3p

The mechanisms of colorectal cancer cell mesenchymal-epithelial transition induced by hepatocyte exosome-derived miR-203a-3p

Abstract Background Liver metastasis is the most common cause of death in patients with colorectal cancer (CRC). Phosphatase of regenerating liver-3 induces CRC metastasis by epithelial-to-mesenchymal transition, which promotes CRC cell liver metastasis. Mesenchymal-to-epithelial transition (MET), t...

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Bibliographic Details
Main Authors: Heyang Xu, Qiusheng Lan, Yongliang Huang, Yang Zhang, Yujie Zeng, Pengwei Su, Ziqiang Chu, Wei Lai, Zhonghua Chu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Cancer
Subjects:
miR-203a-3p
Exosome
Mesenchymal-to-epithelial transition
Colorectal cancer
Online Access:https://doi.org/10.1186/s12885-021-08419-x

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