UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway

UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway

Abstract Background Ovarian cancer is the most lethal gynecologic malignancy worldwide. Olaparib, an inhibitor of poly (ADP-ribose) polymerase (PARP), is becoming widely used in ovarian cancer treatment. The overall survival of ovarian cancer has not been significantly changed over the past decades...

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Bibliographic Details
Main Authors: Wenjing Hu, Min Li, Youguo Chen, Xinxian Gu
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Ovarian Research
Subjects:
Ovarian Cancer
UBE2S
Olaparib
Wnt/β-catenin
Online Access:https://doi.org/10.1186/s13048-021-00877-y

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