High molecular weight heparin-induced angiogenesis mainly mediated via basic fibroblast growth factor-2- an in-vivo (CAM) and in-silico analysis

High molecular weight heparin-induced angiogenesis mainly mediated via basic fibroblast growth factor-2- an in-vivo (CAM) and in-silico analysis

Background: High-molecular weight heparin (HMWH), a molecule extensively used as an anticoagulant, shows concentration-dependent angiogenic and anti-angiogenic potential. So far, no studies have reported the interactive potential of HMWH with various pro-angiogenic growth factors under physiological...

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Bibliographic Details
Main Authors: Reji Manjunathan, Kartik Mitra, Rahul Vasvani, Mukesh Doble
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
High-molecular weight heparin
HMWH
Fibroblast growth factor
FGF2
Matrix metalloproteinase 2- MMP2
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823001905

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