Structures of Reaction Products and Degradation Pathways of Aflatoxin B<sub>1</sub> by Ultrasound Treatment
Ultrasound is an emerging decontamination technology with potential use in the global food processing industry. In the present study, we explored power ultrasound for processing aqueous aflatoxin B<sub>1</sub> (AFB<sub>1</sub>). AFB<sub>1</sub> was degraded by 85....
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| Format: | Article |
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MDPI AG
2019-09-01
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| Series: | Toxins |
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| Online Access: | https://www.mdpi.com/2072-6651/11/9/526 |
| _version_ | 1818001697726791680 |
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| author | Yuanfang Liu Mengmeng Li Yuanxiao Liu Ke Bian |
| author_facet | Yuanfang Liu Mengmeng Li Yuanxiao Liu Ke Bian |
| author_sort | Yuanfang Liu |
| collection | DOAJ |
| description | Ultrasound is an emerging decontamination technology with potential use in the global food processing industry. In the present study, we explored power ultrasound for processing aqueous aflatoxin B<sub>1</sub> (AFB<sub>1</sub>). AFB<sub>1</sub> was degraded by 85.1% after 80 min of ultrasound exposure. The reaction products of AFB<sub>1</sub> were identified and their molecular formulae elucidated by ultra-high-performance liquid chromatography Q-Orbitrap mass spectrometry. Eight main reaction products were found, and their structures were clarified by parental ion fragmentation. Two degradation pathways were proposed according to the degradation product structures: One involved the addition of H• and OH• radicals, whereas the other involved H<sub>2</sub>O<sub>2</sub> epoxidation and H•, OH•, and H<sub>2</sub>O<sub>2</sub> oxidation of AFB<sub>1</sub>. Ultrasound treatment significantly reduced AFB<sub>1</sub> bioactivity and toxicity by disrupting the C8=C9 double bond in the furan ring and modifying the lactone ring and methoxy group. |
| first_indexed | 2024-04-14T03:36:35Z |
| format | Article |
| id | doaj.art-4797b8e15a0a4b40a617810c0884244b |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-04-14T03:36:35Z |
| publishDate | 2019-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-4797b8e15a0a4b40a617810c0884244b2022-12-22T02:14:43ZengMDPI AGToxins2072-66512019-09-0111952610.3390/toxins11090526toxins11090526Structures of Reaction Products and Degradation Pathways of Aflatoxin B<sub>1</sub> by Ultrasound TreatmentYuanfang Liu0Mengmeng Li1Yuanxiao Liu2Ke Bian3College of Food Science and Technology, Henan University of Technology, Zhengzhou 450001, ChinaCollege of Food Science and Technology, Henan University of Technology, Zhengzhou 450001, ChinaCollege of Food Science and Technology, Henan University of Technology, Zhengzhou 450001, ChinaCollege of Food Science and Technology, Henan University of Technology, Zhengzhou 450001, ChinaUltrasound is an emerging decontamination technology with potential use in the global food processing industry. In the present study, we explored power ultrasound for processing aqueous aflatoxin B<sub>1</sub> (AFB<sub>1</sub>). AFB<sub>1</sub> was degraded by 85.1% after 80 min of ultrasound exposure. The reaction products of AFB<sub>1</sub> were identified and their molecular formulae elucidated by ultra-high-performance liquid chromatography Q-Orbitrap mass spectrometry. Eight main reaction products were found, and their structures were clarified by parental ion fragmentation. Two degradation pathways were proposed according to the degradation product structures: One involved the addition of H• and OH• radicals, whereas the other involved H<sub>2</sub>O<sub>2</sub> epoxidation and H•, OH•, and H<sub>2</sub>O<sub>2</sub> oxidation of AFB<sub>1</sub>. Ultrasound treatment significantly reduced AFB<sub>1</sub> bioactivity and toxicity by disrupting the C8=C9 double bond in the furan ring and modifying the lactone ring and methoxy group.https://www.mdpi.com/2072-6651/11/9/526reaction productsaflatoxin B<sub>1</sub>UHPLC-Orbitrap-MSultrasound treatment |
| spellingShingle | Yuanfang Liu Mengmeng Li Yuanxiao Liu Ke Bian Structures of Reaction Products and Degradation Pathways of Aflatoxin B<sub>1</sub> by Ultrasound Treatment Toxins reaction products aflatoxin B<sub>1</sub> UHPLC-Orbitrap-MS ultrasound treatment |
| title | Structures of Reaction Products and Degradation Pathways of Aflatoxin B<sub>1</sub> by Ultrasound Treatment |
| title_full | Structures of Reaction Products and Degradation Pathways of Aflatoxin B<sub>1</sub> by Ultrasound Treatment |
| title_fullStr | Structures of Reaction Products and Degradation Pathways of Aflatoxin B<sub>1</sub> by Ultrasound Treatment |
| title_full_unstemmed | Structures of Reaction Products and Degradation Pathways of Aflatoxin B<sub>1</sub> by Ultrasound Treatment |
| title_short | Structures of Reaction Products and Degradation Pathways of Aflatoxin B<sub>1</sub> by Ultrasound Treatment |
| title_sort | structures of reaction products and degradation pathways of aflatoxin b sub 1 sub by ultrasound treatment |
| topic | reaction products aflatoxin B<sub>1</sub> UHPLC-Orbitrap-MS ultrasound treatment |
| url | https://www.mdpi.com/2072-6651/11/9/526 |
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