Familial Adenomatous Polyposis with Synchronous Invasive Colonic Carcinomas and Metastatic Jejunal Adenocarcinoma in a Nigerian Male
Familial adenomatous polyposis is rare. Three cases were previously reported in Nigeria. An intriguing feature of this case is an ulcerated jejunal carcinoma which was metastatic rather than synchronous carcinoma. This patient presented with partial large bowel obstruction and the pathological analy...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2010-12-01
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| Series: | Rare Tumors |
| Online Access: | https://doi.org/10.4081/rt-2010-4-e66 |
| _version_ | 1828525599873826816 |
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| author | Chukwuemeka C. Osuagwu Okechukwu C. Okafor Emmanuel R. Ezeome Chrisogonus E. Uche Charles Ememonu Emeka Kesieme |
| author_facet | Chukwuemeka C. Osuagwu Okechukwu C. Okafor Emmanuel R. Ezeome Chrisogonus E. Uche Charles Ememonu Emeka Kesieme |
| author_sort | Chukwuemeka C. Osuagwu |
| collection | DOAJ |
| description | Familial adenomatous polyposis is rare. Three cases were previously reported in Nigeria. An intriguing feature of this case is an ulcerated jejunal carcinoma which was metastatic rather than synchronous carcinoma. This patient presented with partial large bowel obstruction and the pathological analysis revealed 4 invasive adenocarcinomas, 3 in the colon and 1 in the jejunum (Dukes stage D). Palliative pancolectomy and jejunal tumour resection with chemotherapy was offered to him. He died eight months after surgery from disease progression. The challenges of managing a hereditary cancer syndrome in a resource poor country are highlighted. |
| first_indexed | 2024-12-11T21:09:43Z |
| format | Article |
| id | doaj.art-479903573d75454b9d7bf9f5fe514c6c |
| institution | Directory Open Access Journal |
| issn | 2036-3613 |
| language | English |
| last_indexed | 2024-12-11T21:09:43Z |
| publishDate | 2010-12-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Rare Tumors |
| spelling | doaj.art-479903573d75454b9d7bf9f5fe514c6c2022-12-22T00:50:46ZengSAGE PublishingRare Tumors2036-36132010-12-01210.4081/rt-2010-4-e66Familial Adenomatous Polyposis with Synchronous Invasive Colonic Carcinomas and Metastatic Jejunal Adenocarcinoma in a Nigerian MaleChukwuemeka C. Osuagwu0Okechukwu C. Okafor1Emmanuel R. Ezeome2Chrisogonus E. Uche3Charles Ememonu4Emeka Kesieme5 Department of Surgery, Imo State University Teaching Hospital, Orlu, Imo state, Nigeria Department of Morbid Anatomy, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria Department of Surgery, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria Department of Surgery, Imo State University Teaching Hospital, Orlu, Imo state, Nigeria Department of Surgery, Imo State University Teaching Hospital, Orlu, Imo state, Nigeria Department of Surgery, Imo State University Teaching Hospital, Orlu, Imo state, NigeriaFamilial adenomatous polyposis is rare. Three cases were previously reported in Nigeria. An intriguing feature of this case is an ulcerated jejunal carcinoma which was metastatic rather than synchronous carcinoma. This patient presented with partial large bowel obstruction and the pathological analysis revealed 4 invasive adenocarcinomas, 3 in the colon and 1 in the jejunum (Dukes stage D). Palliative pancolectomy and jejunal tumour resection with chemotherapy was offered to him. He died eight months after surgery from disease progression. The challenges of managing a hereditary cancer syndrome in a resource poor country are highlighted.https://doi.org/10.4081/rt-2010-4-e66 |
| spellingShingle | Chukwuemeka C. Osuagwu Okechukwu C. Okafor Emmanuel R. Ezeome Chrisogonus E. Uche Charles Ememonu Emeka Kesieme Familial Adenomatous Polyposis with Synchronous Invasive Colonic Carcinomas and Metastatic Jejunal Adenocarcinoma in a Nigerian Male Rare Tumors |
| title | Familial Adenomatous Polyposis with Synchronous Invasive Colonic
Carcinomas and Metastatic Jejunal Adenocarcinoma in a Nigerian
Male |
| title_full | Familial Adenomatous Polyposis with Synchronous Invasive Colonic
Carcinomas and Metastatic Jejunal Adenocarcinoma in a Nigerian
Male |
| title_fullStr | Familial Adenomatous Polyposis with Synchronous Invasive Colonic
Carcinomas and Metastatic Jejunal Adenocarcinoma in a Nigerian
Male |
| title_full_unstemmed | Familial Adenomatous Polyposis with Synchronous Invasive Colonic
Carcinomas and Metastatic Jejunal Adenocarcinoma in a Nigerian
Male |
| title_short | Familial Adenomatous Polyposis with Synchronous Invasive Colonic
Carcinomas and Metastatic Jejunal Adenocarcinoma in a Nigerian
Male |
| title_sort | familial adenomatous polyposis with synchronous invasive colonic carcinomas and metastatic jejunal adenocarcinoma in a nigerian male |
| url | https://doi.org/10.4081/rt-2010-4-e66 |
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