Anemia aplástica. Tratamento alternativo à transplantação medular.
We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ordem dos Médicos
1997-01-01
|
| Series: | Acta Médica Portuguesa |
| Online Access: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372 |
| _version_ | 1828106242237661184 |
|---|---|
| author | T Fonseca J Raposo B Gomez J J d'Oliveira J M de Lacerda |
| author_facet | T Fonseca J Raposo B Gomez J J d'Oliveira J M de Lacerda |
| author_sort | T Fonseca |
| collection | DOAJ |
| description | We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed. |
| first_indexed | 2024-04-11T10:13:47Z |
| format | Article |
| id | doaj.art-479a0c53309640e299353bb5aca466ff |
| institution | Directory Open Access Journal |
| issn | 0870-399X 1646-0758 |
| language | English |
| last_indexed | 2024-04-11T10:13:47Z |
| publishDate | 1997-01-01 |
| publisher | Ordem dos Médicos |
| record_format | Article |
| series | Acta Médica Portuguesa |
| spelling | doaj.art-479a0c53309640e299353bb5aca466ff2022-12-22T04:30:00ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07581997-01-0110110.20344/amp.2372Anemia aplástica. Tratamento alternativo à transplantação medular.T Fonseca0J RaposoB GomezJ J d'OliveiraJ M de LacerdaServiço Medicina I, Hospital de Santa maria, Lisboa.We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372 |
| spellingShingle | T Fonseca J Raposo B Gomez J J d'Oliveira J M de Lacerda Anemia aplástica. Tratamento alternativo à transplantação medular. Acta Médica Portuguesa |
| title | Anemia aplástica. Tratamento alternativo à transplantação medular. |
| title_full | Anemia aplástica. Tratamento alternativo à transplantação medular. |
| title_fullStr | Anemia aplástica. Tratamento alternativo à transplantação medular. |
| title_full_unstemmed | Anemia aplástica. Tratamento alternativo à transplantação medular. |
| title_short | Anemia aplástica. Tratamento alternativo à transplantação medular. |
| title_sort | anemia aplastica tratamento alternativo a transplantacao medular |
| url | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372 |
| work_keys_str_mv | AT tfonseca anemiaaplasticatratamentoalternativoatransplantacaomedular AT jraposo anemiaaplasticatratamentoalternativoatransplantacaomedular AT bgomez anemiaaplasticatratamentoalternativoatransplantacaomedular AT jjdoliveira anemiaaplasticatratamentoalternativoatransplantacaomedular AT jmdelacerda anemiaaplasticatratamentoalternativoatransplantacaomedular |