Assessment of Current Trends in Demographic and Clinical Characteristics of Male Patients with Rheumatoid Arthritis: A Retrospective Study
Introduction: Role of gender in development of an autoimmune dysfunction in Rheumatoid Arthritis (RA) is very complex and therefore novel concept of gender medicine has come into limelight. Aim: To assess current trends in demographic and clinical characteristics of male patients with RA. Mate...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2022-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/17098/58811_CE(AnK)_F[SK]_PF1(SC_SHU)_PFA(SS)_PB(SC_SS)_PN(SS).pdf |
| _version_ | 1797946975372443648 |
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| author | Bharat Kumar Singh Seema Singh |
| author_facet | Bharat Kumar Singh Seema Singh |
| author_sort | Bharat Kumar Singh |
| collection | DOAJ |
| description | Introduction: Role of gender in development of an autoimmune
dysfunction in Rheumatoid Arthritis (RA) is very complex and
therefore novel concept of gender medicine has come into
limelight.
Aim: To assess current trends in demographic and clinical
characteristics of male patients with RA.
Materials and Methods: This retrospective study was conducted
among patients with RA attending Outpatient Department of
Rheumatology at Santokba Durlabhji Memorial Hospital cum
medical Research Institute, Jaipur and Centre for Arthritis and
Autoimmune Rheumatic Disorders, Jaipur, Rajasthan, India,
during April 2015 to April 2021. Men who qualified the European
League Against Rheumatism (EULAR)/American College of
Rheumatology (ACR) criteria for RA were included in this study.
The medical records of patients were reviewed for collecting demographic and clinical characteristics, disease activity,
disease duration, deformities, extra articular manifestations, and
co-morbid illness.
Results: A total of 179 men were enrolled, and the mean age was
45.3±11.1 years. The majority of patients had severe disease with
more than two years of disease duration. Subcutaneous nodule
(27.8%) was most frequently observed extra-articular manifestations.
Rheumatoid factor positivity and cyclic citrullinated peptide were
prevalent in 107 and 110 patients, respectively. Osteoporosis
(21.1%) and hypertension (19.2%) were the most common comorbidities and majority of patients reported wrist deformities.
Conclusion: Overall observations indicate the presence of
subcutaneous nodule as the common extra-articular manifestation
with more than 2 years of disease duration, osteoporosis and
hypertension as the most common co-morbidities; and high
prevalence of wrist deformities in male patients with RA. |
| first_indexed | 2024-04-10T21:20:33Z |
| format | Article |
| id | doaj.art-479b44f825ea4cdb877add26c5af92f7 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-10T21:20:33Z |
| publishDate | 2022-10-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-479b44f825ea4cdb877add26c5af92f72023-01-20T05:29:12ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-10-011610OC31OC3410.7860/JCDR/2022/58811.17098Assessment of Current Trends in Demographic and Clinical Characteristics of Male Patients with Rheumatoid Arthritis: A Retrospective StudyBharat Kumar Singh0Seema Singh1Consultant Rheumatologist, Department of Rheumatology, Santokba Durlabhji Memorial Hospital and Medical Research Institute, Jaipur, Rajasthan, India.Assistant Professor, Department of Pathology, Rajasthan University of Health Sciences, Jaipur, Rajasthan, India.Introduction: Role of gender in development of an autoimmune dysfunction in Rheumatoid Arthritis (RA) is very complex and therefore novel concept of gender medicine has come into limelight. Aim: To assess current trends in demographic and clinical characteristics of male patients with RA. Materials and Methods: This retrospective study was conducted among patients with RA attending Outpatient Department of Rheumatology at Santokba Durlabhji Memorial Hospital cum medical Research Institute, Jaipur and Centre for Arthritis and Autoimmune Rheumatic Disorders, Jaipur, Rajasthan, India, during April 2015 to April 2021. Men who qualified the European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) criteria for RA were included in this study. The medical records of patients were reviewed for collecting demographic and clinical characteristics, disease activity, disease duration, deformities, extra articular manifestations, and co-morbid illness. Results: A total of 179 men were enrolled, and the mean age was 45.3±11.1 years. The majority of patients had severe disease with more than two years of disease duration. Subcutaneous nodule (27.8%) was most frequently observed extra-articular manifestations. Rheumatoid factor positivity and cyclic citrullinated peptide were prevalent in 107 and 110 patients, respectively. Osteoporosis (21.1%) and hypertension (19.2%) were the most common comorbidities and majority of patients reported wrist deformities. Conclusion: Overall observations indicate the presence of subcutaneous nodule as the common extra-articular manifestation with more than 2 years of disease duration, osteoporosis and hypertension as the most common co-morbidities; and high prevalence of wrist deformities in male patients with RA.https://www.jcdr.net/articles/PDF/17098/58811_CE(AnK)_F[SK]_PF1(SC_SHU)_PFA(SS)_PB(SC_SS)_PN(SS).pdfhypertensionosteoporosissubcutaneous nodule |
| spellingShingle | Bharat Kumar Singh Seema Singh Assessment of Current Trends in Demographic and Clinical Characteristics of Male Patients with Rheumatoid Arthritis: A Retrospective Study Journal of Clinical and Diagnostic Research hypertension osteoporosis subcutaneous nodule |
| title | Assessment of Current Trends in Demographic and Clinical Characteristics of Male Patients with Rheumatoid Arthritis: A Retrospective Study |
| title_full | Assessment of Current Trends in Demographic and Clinical Characteristics of Male Patients with Rheumatoid Arthritis: A Retrospective Study |
| title_fullStr | Assessment of Current Trends in Demographic and Clinical Characteristics of Male Patients with Rheumatoid Arthritis: A Retrospective Study |
| title_full_unstemmed | Assessment of Current Trends in Demographic and Clinical Characteristics of Male Patients with Rheumatoid Arthritis: A Retrospective Study |
| title_short | Assessment of Current Trends in Demographic and Clinical Characteristics of Male Patients with Rheumatoid Arthritis: A Retrospective Study |
| title_sort | assessment of current trends in demographic and clinical characteristics of male patients with rheumatoid arthritis a retrospective study |
| topic | hypertension osteoporosis subcutaneous nodule |
| url | https://www.jcdr.net/articles/PDF/17098/58811_CE(AnK)_F[SK]_PF1(SC_SHU)_PFA(SS)_PB(SC_SS)_PN(SS).pdf |
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