ACTIVATION OF HUMAN BLOOD MONONUCLEARS BY LIPOPOLYSACCHARIDE OF DIFFERENT COMPOSITION

Influence of lipopolysaccharide (LPS) composition upon activation of human blood mononuclears was investigated, by measuring levels of pro-inflammatory TNFα and IL-6 cytokines released by the cells. It is shown that LPS from Rhodobacter capsulatus PG, in contrast to E. coli LPS, did not activate the...

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Main Authors: S. V. Zubova, E. V. Voloshina, N. I. Kosjakova, S. V. Grachev, I. R Prokhorenko
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:Медицинская иммунология
Subjects:
Online Access:https://www.mimmun.ru/mimmun/article/view/220
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author S. V. Zubova
E. V. Voloshina
N. I. Kosjakova
S. V. Grachev
I. R Prokhorenko
author_facet S. V. Zubova
E. V. Voloshina
N. I. Kosjakova
S. V. Grachev
I. R Prokhorenko
author_sort S. V. Zubova
collection DOAJ
description Influence of lipopolysaccharide (LPS) composition upon activation of human blood mononuclears was investigated, by measuring levels of pro-inflammatory TNFα and IL-6 cytokines released by the cells. It is shown that LPS from Rhodobacter capsulatus PG, in contrast to E. coli LPS, did not activate the target cells for synthesis of the cytokines.
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language Russian
last_indexed 2025-03-14T02:21:06Z
publishDate 2014-07-01
publisher St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
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series Медицинская иммунология
spelling doaj.art-479f69a1561d4b2c95c503014a9036fe2025-03-11T17:59:01ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-01124-540540810.15789/1563-0625-2010-4-5-405-408217ACTIVATION OF HUMAN BLOOD MONONUCLEARS BY LIPOPOLYSACCHARIDE OF DIFFERENT COMPOSITIONS. V. Zubova0E. V. Voloshina1N. I. Kosjakova2S. V. Grachev3I. R Prokhorenko4Институт фундаментальных проблем биологии РАН, г. Пущино, Московская областьИнститут фундаментальных проблем биологии РАН, г. Пущино, Московская областьОтделение аллергологии и иммунологии ПНЦ РАН, г. Пущино, Московская областьМосковская медицинская академия им. И.М. Сеченова, МоскваИнститут фундаментальных проблем биологии РАН, г. Пущино, Московская областьInfluence of lipopolysaccharide (LPS) composition upon activation of human blood mononuclears was investigated, by measuring levels of pro-inflammatory TNFα and IL-6 cytokines released by the cells. It is shown that LPS from Rhodobacter capsulatus PG, in contrast to E. coli LPS, did not activate the target cells for synthesis of the cytokines.https://www.mimmun.ru/mimmun/article/view/220cytokineslipopolysaccharideshuman blood mononuclear cellsblood serum
spellingShingle S. V. Zubova
E. V. Voloshina
N. I. Kosjakova
S. V. Grachev
I. R Prokhorenko
ACTIVATION OF HUMAN BLOOD MONONUCLEARS BY LIPOPOLYSACCHARIDE OF DIFFERENT COMPOSITION
Медицинская иммунология
cytokines
lipopolysaccharides
human blood mononuclear cells
blood serum
title ACTIVATION OF HUMAN BLOOD MONONUCLEARS BY LIPOPOLYSACCHARIDE OF DIFFERENT COMPOSITION
title_full ACTIVATION OF HUMAN BLOOD MONONUCLEARS BY LIPOPOLYSACCHARIDE OF DIFFERENT COMPOSITION
title_fullStr ACTIVATION OF HUMAN BLOOD MONONUCLEARS BY LIPOPOLYSACCHARIDE OF DIFFERENT COMPOSITION
title_full_unstemmed ACTIVATION OF HUMAN BLOOD MONONUCLEARS BY LIPOPOLYSACCHARIDE OF DIFFERENT COMPOSITION
title_short ACTIVATION OF HUMAN BLOOD MONONUCLEARS BY LIPOPOLYSACCHARIDE OF DIFFERENT COMPOSITION
title_sort activation of human blood mononuclears by lipopolysaccharide of different composition
topic cytokines
lipopolysaccharides
human blood mononuclear cells
blood serum
url https://www.mimmun.ru/mimmun/article/view/220
work_keys_str_mv AT svzubova activationofhumanbloodmononuclearsbylipopolysaccharideofdifferentcomposition
AT evvoloshina activationofhumanbloodmononuclearsbylipopolysaccharideofdifferentcomposition
AT nikosjakova activationofhumanbloodmononuclearsbylipopolysaccharideofdifferentcomposition
AT svgrachev activationofhumanbloodmononuclearsbylipopolysaccharideofdifferentcomposition
AT irprokhorenko activationofhumanbloodmononuclearsbylipopolysaccharideofdifferentcomposition