Application of Piezoelectric Material and Devices in Bone Regeneration
Bone injuries are common in clinical practice. Given the clear disadvantages of autologous bone grafting, more efficient and safer bone grafts need to be developed. Bone is a multidirectional and anisotropic piezoelectric material that exhibits an electrical microenvironment; therefore, electrical s...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/24/4386 |
| _version_ | 1827637450988584960 |
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| author | Chunyu Yang Jianying Ji Yujia Lv Zhou Li Dan Luo |
| author_facet | Chunyu Yang Jianying Ji Yujia Lv Zhou Li Dan Luo |
| author_sort | Chunyu Yang |
| collection | DOAJ |
| description | Bone injuries are common in clinical practice. Given the clear disadvantages of autologous bone grafting, more efficient and safer bone grafts need to be developed. Bone is a multidirectional and anisotropic piezoelectric material that exhibits an electrical microenvironment; therefore, electrical signals play a very important role in the process of bone repair, which can effectively promote osteoblast differentiation, migration, and bone regeneration. Piezoelectric materials can generate electricity under mechanical stress without requiring an external power supply; therefore, using it as a bone implant capable of harnessing the body’s kinetic energy to generate the electrical signals needed for bone growth is very promising for bone regeneration. At the same time, devices composed of piezoelectric material using electromechanical conversion technology can effectively monitor the structural health of bone, which facilitates the adjustment of the treatment plan at any time. In this paper, the mechanism and classification of piezoelectric materials and their applications in the cell, tissue, sensing, and repair indicator monitoring aspects in the process of bone regeneration are systematically reviewed. |
| first_indexed | 2024-03-09T16:01:11Z |
| format | Article |
| id | doaj.art-479fc6d2a5914520b3c1f0310e6ddf1a |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T16:01:11Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-479fc6d2a5914520b3c1f0310e6ddf1a2023-11-24T17:03:29ZengMDPI AGNanomaterials2079-49912022-12-011224438610.3390/nano12244386Application of Piezoelectric Material and Devices in Bone RegenerationChunyu Yang0Jianying Ji1Yujia Lv2Zhou Li3Dan Luo4Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083, ChinaBeijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083, ChinaBeijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083, ChinaBeijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083, ChinaBeijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083, ChinaBone injuries are common in clinical practice. Given the clear disadvantages of autologous bone grafting, more efficient and safer bone grafts need to be developed. Bone is a multidirectional and anisotropic piezoelectric material that exhibits an electrical microenvironment; therefore, electrical signals play a very important role in the process of bone repair, which can effectively promote osteoblast differentiation, migration, and bone regeneration. Piezoelectric materials can generate electricity under mechanical stress without requiring an external power supply; therefore, using it as a bone implant capable of harnessing the body’s kinetic energy to generate the electrical signals needed for bone growth is very promising for bone regeneration. At the same time, devices composed of piezoelectric material using electromechanical conversion technology can effectively monitor the structural health of bone, which facilitates the adjustment of the treatment plan at any time. In this paper, the mechanism and classification of piezoelectric materials and their applications in the cell, tissue, sensing, and repair indicator monitoring aspects in the process of bone regeneration are systematically reviewed.https://www.mdpi.com/2079-4991/12/24/4386piezoelectric materialselectrical stimulationdevicesbiomedical engineering applications |
| spellingShingle | Chunyu Yang Jianying Ji Yujia Lv Zhou Li Dan Luo Application of Piezoelectric Material and Devices in Bone Regeneration Nanomaterials piezoelectric materials electrical stimulation devices biomedical engineering applications |
| title | Application of Piezoelectric Material and Devices in Bone Regeneration |
| title_full | Application of Piezoelectric Material and Devices in Bone Regeneration |
| title_fullStr | Application of Piezoelectric Material and Devices in Bone Regeneration |
| title_full_unstemmed | Application of Piezoelectric Material and Devices in Bone Regeneration |
| title_short | Application of Piezoelectric Material and Devices in Bone Regeneration |
| title_sort | application of piezoelectric material and devices in bone regeneration |
| topic | piezoelectric materials electrical stimulation devices biomedical engineering applications |
| url | https://www.mdpi.com/2079-4991/12/24/4386 |
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