Difference in the relative biological effectiveness and DNA damage repair processes in response to proton beam therapy according to the positions of the spread out Bragg peak

Difference in the relative biological effectiveness and DNA damage repair processes in response to proton beam therapy according to the positions of the spread out Bragg peak

Abstract Background Cellular responses to proton beam irradiation are not yet clearly understood, especially differences in the relative biological effectiveness (RBE) of high-energy proton beams depending on the position on the Spread-Out Bragg Peak (SOBP). Towards this end, we investigated the dif...

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Bibliographic Details
Main Authors: Hidehiro Hojo, Takeshi Dohmae, Kenji Hotta, Ryosuke Kohno, Atsushi Motegi, Atsushi Yagishita, Hideki Makinoshima, Katsuya Tsuchihara, Tetsuo Akimoto
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Radiation Oncology
Subjects:
Proton beam
Relative Biological Effectiveness
Linear Energy Transfer
Spread-Out Bragg Peak
DNA damage
Online Access:http://link.springer.com/article/10.1186/s13014-017-0849-1

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