MORPHOLOGY OF TUBERCULOSIS CONCURRENT WITH HIV INFECTION: POSTMORTEM DATA
The pathomorphology of tuberculosis was studied in 129 deceased patients with concomitant HIV infection and in 50 patients with acutely progressive forms of the disease (a comparison group). In tuberculosis concurrent with HIV infection, the morphological pattern in the lung and other viscera depend...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
New Terra Publishing House
2014-10-01
|
| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/295 |
| _version_ | 1797700213342732288 |
|---|---|
| author | A. M. Mikhailovsky L. N. Lepekha V. V. Erokhin |
| author_facet | A. M. Mikhailovsky L. N. Lepekha V. V. Erokhin |
| author_sort | A. M. Mikhailovsky |
| collection | DOAJ |
| description | The pathomorphology of tuberculosis was studied in 129 deceased patients with concomitant HIV infection and in 50 patients with acutely progressive forms of the disease (a comparison group). In tuberculosis concurrent with HIV infection, the morphological pattern in the lung and other viscera depends on the primacy of a lesion and reflects the progressive pattern of specific inflammation. In the TB-HIV group, the signs of a pre-existing specific process with foci of fibrosis and hyalinosis, a mild or moderate granulomatous reaction with epithelioid cells always persist in the lung. The tuberculous process progresses due to lymphohematogenic and bronchogenic dissemination. The HIV-TB group is characterized by the preponderance of exudative and alterative changes, the absence of signs of separation and organization of inflammatory pyonecrotic foci having no signs of specificity in the lung and other viscera. Progression of tuberculous inflammation occurs mainly by hematogenic dissemination. In all the observed groups, there is lymphadenopathy that appears as caseuos necrosis in the TB-HIV group and reactive hyperplasia in the HIV-TB group. |
| first_indexed | 2024-03-12T04:18:51Z |
| format | Article |
| id | doaj.art-47a10f731b1c474b9689931682acf6c6 |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2024-03-12T04:18:51Z |
| publishDate | 2014-10-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-47a10f731b1c474b9689931682acf6c62023-09-03T10:34:28ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062014-10-01010657010.21292/2075-1230-2014-0-10-65-70295MORPHOLOGY OF TUBERCULOSIS CONCURRENT WITH HIV INFECTION: POSTMORTEM DATAA. M. Mikhailovsky0L. N. Lepekha1V. V. Erokhin2ГБУЗ «Оренбургский областной клинический противотуберкулезный диспансер»ФГБУ «Центральный НИИ туберкулеза» РАМН, г. МоскваФГБУ «Центральный НИИ туберкулеза» РАМН, г. МоскваThe pathomorphology of tuberculosis was studied in 129 deceased patients with concomitant HIV infection and in 50 patients with acutely progressive forms of the disease (a comparison group). In tuberculosis concurrent with HIV infection, the morphological pattern in the lung and other viscera depends on the primacy of a lesion and reflects the progressive pattern of specific inflammation. In the TB-HIV group, the signs of a pre-existing specific process with foci of fibrosis and hyalinosis, a mild or moderate granulomatous reaction with epithelioid cells always persist in the lung. The tuberculous process progresses due to lymphohematogenic and bronchogenic dissemination. The HIV-TB group is characterized by the preponderance of exudative and alterative changes, the absence of signs of separation and organization of inflammatory pyonecrotic foci having no signs of specificity in the lung and other viscera. Progression of tuberculous inflammation occurs mainly by hematogenic dissemination. In all the observed groups, there is lymphadenopathy that appears as caseuos necrosis in the TB-HIV group and reactive hyperplasia in the HIV-TB group.https://www.tibl-journal.com/jour/article/view/295туберкулезвич-инфекциягранулематозная реакцияказеозный некрозгенерализованный туберкулез |
| spellingShingle | A. M. Mikhailovsky L. N. Lepekha V. V. Erokhin MORPHOLOGY OF TUBERCULOSIS CONCURRENT WITH HIV INFECTION: POSTMORTEM DATA Туберкулез и болезни лёгких туберкулез вич-инфекция гранулематозная реакция казеозный некроз генерализованный туберкулез |
| title | MORPHOLOGY OF TUBERCULOSIS CONCURRENT WITH HIV INFECTION: POSTMORTEM DATA |
| title_full | MORPHOLOGY OF TUBERCULOSIS CONCURRENT WITH HIV INFECTION: POSTMORTEM DATA |
| title_fullStr | MORPHOLOGY OF TUBERCULOSIS CONCURRENT WITH HIV INFECTION: POSTMORTEM DATA |
| title_full_unstemmed | MORPHOLOGY OF TUBERCULOSIS CONCURRENT WITH HIV INFECTION: POSTMORTEM DATA |
| title_short | MORPHOLOGY OF TUBERCULOSIS CONCURRENT WITH HIV INFECTION: POSTMORTEM DATA |
| title_sort | morphology of tuberculosis concurrent with hiv infection postmortem data |
| topic | туберкулез вич-инфекция гранулематозная реакция казеозный некроз генерализованный туберкулез |
| url | https://www.tibl-journal.com/jour/article/view/295 |
| work_keys_str_mv | AT ammikhailovsky morphologyoftuberculosisconcurrentwithhivinfectionpostmortemdata AT lnlepekha morphologyoftuberculosisconcurrentwithhivinfectionpostmortemdata AT vverokhin morphologyoftuberculosisconcurrentwithhivinfectionpostmortemdata |