A Common Polymorphism in <i>RNASE6</i> Impacts Its Antimicrobial Activity toward Uropathogenic <i>Escherichia coli</i>

A Common Polymorphism in <i>RNASE6</i> Impacts Its Antimicrobial Activity toward Uropathogenic <i>Escherichia coli</i>

Human Ribonuclease (RNase) 6 is a monocyte and macrophage-derived protein with potent antimicrobial activity toward uropathogenic bacteria. The <i>RNASE6</i> gene is heterogeneous in humans due to the presence of single nucleotide polymorphisms (SNPs). <i>RNASE6</i> rs1045922...

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Bibliographic Details
Main Authors: Raul Anguita, Guillem Prats-Ejarque, Mohammed Moussaoui, Brian Becknell, Ester Boix
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
RNase
RNase 6
RNase k6
single nucleotide polymorphisms
antimicrobial peptides
urinary tract infections
Online Access:https://www.mdpi.com/1422-0067/25/1/604

Internet

https://www.mdpi.com/1422-0067/25/1/604

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