In vitro anti-Candida activity and single crystal X-ray structure of ({(1E)-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]amino}oxy)(4-nitrophenyl)methanone

In vitro anti-Candida activity and single crystal X-ray structure of ({(1E)-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]amino}oxy)(4-nitrophenyl)methanone

Synthesis, characterization, and anti-Candida activity of ({(E)-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]amino}oxy)(4-nitrophenyl)methanone (4) are reported. Compound 4 showed anti-Candida albicans activity (MIC = 0.6862 µmol/mL) being nearly 5-fold more potent than the gold standard antifungal dru...

Full description

Bibliographic Details
Main Authors: Mohamed I. Attia, Hazem A. Ghabbour, Azza S. Zakaria, Hoong-Kun Fun
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2014-01-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Anti-Candida
Azoles
X-ray
Online Access:https://www.banglajol.info/index.php/BJP/article/view/16990

Similar Items

Similar Items