Galanin attenuates β-amyloid (Aβ) toxicity in rat cholinergic basal forebrain neurons

Galanin attenuates β-amyloid (Aβ) toxicity in rat cholinergic basal forebrain neurons

In brains of Alzheimer's disease (AD) patients, expression of the neuropeptide galanin is significantly upregulated and galanin-immunoreactive fibers hypertrophy and hyperinnervate cholinergic neurons of the basal forebrain. However, the role of galanin in AD, whether it is detrimental or neuro...

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Bibliographic Details
Main Authors: Xiling Ding, David MacTavish, Satyabrata Kar, Jack H. Jhamandas
Format: Article
Language:English
Published: Elsevier 2006-02-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
AR-M1896
Diagonal band of Broca
Neuroprotection
Neurodegeneration
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105002275

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