Early changes of bone metabolites and lymphocyte subsets may participate in osteoporosis onset: a preliminary study of a postmenopausal osteoporosis mouse model

Early changes of bone metabolites and lymphocyte subsets may participate in osteoporosis onset: a preliminary study of a postmenopausal osteoporosis mouse model

PurposeMetabolic and immune changes in the early stages of osteoporosis are not well understood. This study aimed to explore the changes in bone metabolites and bone marrow lymphocyte subsets and their relationship during the osteoporosis onset.MethodsWe established OVX and Sham mouse models. After...

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Bibliographic Details
Main Authors: Sizhu Wang, Yuyou Qiu, Cuisong Tang, Huan Tang, Jinchuan Liu, Jieying Chen, Lin Zhang, Guangyu Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Endocrinology
Subjects:
osteoporosis
metabolism
LC-MS/MS
lymphocyte
B cell
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1323647/full

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