Development of a sensitive and specific epitope-blocking ELISA for universal detection of antibodies to human enterovirus 71 strains.

Development of a sensitive and specific epitope-blocking ELISA for universal detection of antibodies to human enterovirus 71 strains.

BACKGROUND: Human Enterovirus 71 (EV71) is a common cause of hand, foot and mouth disease (HFMD) in young children. It is often associated with severe neurological diseases and mortalities in recent outbreaks across the Asia Pacific region. Currently, there is no efficient universal antibody test av...

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Bibliographic Details
Main Authors: Fang He, Tanja K Kiener, Xiao Fang Lim, Yunrui Tan, Kattur Venkatachalam Ashok Raj, Manli Tang, Vincent T K Chow, Qingfeng Chen, Jimmy Kwang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3561296?pdf=render

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