Effects and Mechanisms of Action of Preussin, a Marine Fungal Metabolite, against the Triple-Negative Breast Cancer Cell Line, MDA-MB-231, in 2D and 3D Cultures

Effects and Mechanisms of Action of Preussin, a Marine Fungal Metabolite, against the Triple-Negative Breast Cancer Cell Line, MDA-MB-231, in 2D and 3D Cultures

Triple-negative breast cancer (TNBC) represents an aggressive subtype of breast cancer (BC) with a typically poorer prognosis than other subtypes of BC and limited therapeutic options. Therefore, new drugs would be particularly welcome to help treat TNBC. Preussin, isolated from the marine sponge-as...

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Bibliographic Details
Main Authors:	Rosária Seabra, Fernanda Malhão, Alexandra Correia, Carla Costa, Anake Kijjoa, Eduardo Rocha
Format:	Article
Language:	English
Published:	MDPI AG 2023-03-01
Series:	Marine Drugs
Subjects:	3D cell culture preussin cytotoxicity cancer cells death triple-negative breast cancer
Online Access:	https://www.mdpi.com/1660-3397/21/3/166

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