Fowl adenovirus (FAdV) fiber-based vaccine against inclusion body hepatitis (IBH) provides type-specific protection guided by humoral immunity and regulation of B and T cell response

Fowl adenovirus (FAdV) fiber-based vaccine against inclusion body hepatitis (IBH) provides type-specific protection guided by humoral immunity and regulation of B and T cell response

Abstract A recombinant fowl adenovirus (FAdV) fiber protein, derived from a FAdV-8a strain, was tested for its efficacy to protect chickens against inclusion body hepatitis (IBH). FAdV-E field isolates belonging to both a homotypic (FAdV-8a) and heterotypic (-8b) serotype were used as challenge. Mec...

Full description

Bibliographic Details
Main Authors: Carlotta De Luca, Anna Schachner, Taniya Mitra, Sarah Heidl, Dieter Liebhart, Michael Hess
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Veterinary Research
Subjects:
Fowl adenovirus
fiber
inclusion body hepatitis
vaccine
humoral immunity
cellular immunity
Online Access:https://doi.org/10.1186/s13567-020-00869-8

Similar Items

Similar Items