Synthesis and characterisation of new antimalarial fluorinated triazolopyrazine compounds

Synthesis and characterisation of new antimalarial fluorinated triazolopyrazine compounds

Nine new fluorinated analogues were synthesised by late-stage functionalisation using Diversinate™ chemistry on the Open Source Malaria (OSM) triazolopyrazine scaffold (Series 4). The structures of all analogues were fully characterised by NMR, UV and MS data analysis; three triazolopyrazines were c...

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Bibliographic Details
Main Authors: Kah Yean Lum, Jonathan M. White, Daniel J. G. Johnson, Vicky M. Avery, Rohan A. Davis
Format: Article
Language:English
Published: Beilstein-Institut 2023-01-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
antimalarial
characterisation
diversinatetm
fluorine
triazolopyrazine
scaffold
open source malaria
Online Access:https://doi.org/10.3762/bjoc.19.11

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