3D-printed eye model: Simulation of intraocular pressure
<h4>Purpose</h4> To develop artificial eye models using 3D printing and to evaluate the correlation between different corneal thicknesses and intraocular pressures (IOPs). <h4>Methods</h4> We designed 7 artificial eye models using a computer-aided design system and fabricated...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997944/?tool=EBI |
| _version_ | 1811154314765271040 |
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| author | Hidenaga Kobashi Masaaki Kobayashi |
| author_facet | Hidenaga Kobashi Masaaki Kobayashi |
| author_sort | Hidenaga Kobashi |
| collection | DOAJ |
| description | <h4>Purpose</h4> To develop artificial eye models using 3D printing and to evaluate the correlation between different corneal thicknesses and intraocular pressures (IOPs). <h4>Methods</h4> We designed 7 artificial eye models using a computer-aided design system and fabricated them using 3D printing. Corneal curvature and axial length were based on the Gullstrand eye model. Hydrogels were injected into the vitreous cavity, and seven different corneal thicknesses (200 to 800 μm) were prepared. In this proposed design, we also produced different corneal stiffnesses. A Tono-Pen AVIA tonometer was used by the same examiner to perform five consecutive IOP measurements in each eye model. <h4>Results</h4> Different eye models were ideally created using 3D printing. IOP measurements were successfully performed in each eye model. The corneal thickness was significantly correlated with IOP (R2 = 0.927; 𝑃<0.001). <h4>Conclusion</h4> The 3D-printed eye model is useful for evaluating IOP measurements. This technique might be a promising alternative to the conventional porcine eye model. |
| first_indexed | 2024-04-10T04:13:39Z |
| format | Article |
| id | doaj.art-47b4e354da15417a972fc30264ef870f |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-10T04:13:39Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-47b4e354da15417a972fc30264ef870f2023-03-12T05:32:25ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-011833D-printed eye model: Simulation of intraocular pressureHidenaga KobashiMasaaki Kobayashi<h4>Purpose</h4> To develop artificial eye models using 3D printing and to evaluate the correlation between different corneal thicknesses and intraocular pressures (IOPs). <h4>Methods</h4> We designed 7 artificial eye models using a computer-aided design system and fabricated them using 3D printing. Corneal curvature and axial length were based on the Gullstrand eye model. Hydrogels were injected into the vitreous cavity, and seven different corneal thicknesses (200 to 800 μm) were prepared. In this proposed design, we also produced different corneal stiffnesses. A Tono-Pen AVIA tonometer was used by the same examiner to perform five consecutive IOP measurements in each eye model. <h4>Results</h4> Different eye models were ideally created using 3D printing. IOP measurements were successfully performed in each eye model. The corneal thickness was significantly correlated with IOP (R2 = 0.927; 𝑃<0.001). <h4>Conclusion</h4> The 3D-printed eye model is useful for evaluating IOP measurements. This technique might be a promising alternative to the conventional porcine eye model.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997944/?tool=EBI |
| spellingShingle | Hidenaga Kobashi Masaaki Kobayashi 3D-printed eye model: Simulation of intraocular pressure PLoS ONE |
| title | 3D-printed eye model: Simulation of intraocular pressure |
| title_full | 3D-printed eye model: Simulation of intraocular pressure |
| title_fullStr | 3D-printed eye model: Simulation of intraocular pressure |
| title_full_unstemmed | 3D-printed eye model: Simulation of intraocular pressure |
| title_short | 3D-printed eye model: Simulation of intraocular pressure |
| title_sort | 3d printed eye model simulation of intraocular pressure |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997944/?tool=EBI |
| work_keys_str_mv | AT hidenagakobashi 3dprintedeyemodelsimulationofintraocularpressure AT masaakikobayashi 3dprintedeyemodelsimulationofintraocularpressure |