Baseline CD4+ T cell counts correlates with HIV-1 synonymous rate in HLA-B*5701 subjects with different risk of disease progression.
HLA-B*5701 is the host factor most strongly associated with slow HIV-1 disease progression, although risk of progression may vary among patients carrying this allele. The interplay between HIV-1 evolutionary rate variation and risk of progression to AIDS in HLA-B*5701 subjects was studied using long...
Main Authors: | Melissa M Norström, Nazle M Veras, Wei Huang, Mattia C F Proper, Jennifer Cook, Wendy Hartogensis, Frederick M Hecht, Annika C Karlsson, Marco Salemi |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-09-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4154639?pdf=render |
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