Metabolic and transcriptional activities underlie stationary-phase Pseudomonas aeruginosa sensitivity to Levofloxacin

Metabolic and transcriptional activities underlie stationary-phase Pseudomonas aeruginosa sensitivity to Levofloxacin

ABSTRACT The ubiquitous opportunistic pathogen Pseudomonas aeruginosa is highly adaptive and refractory to several different classes of antibiotics. However, we found in this study that stationary-phase P. aeruginosa cultures exhibit greater sensitivity to the fluoroquinolone Levofloxacin (Levo) tha...

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Bibliographic Details
Main Authors: Patricia J. Hare, Juliet R. Gonzalez, Ryan M. Quelle, Yi I. Wu, Wendy W. K. Mok
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:Microbiology Spectrum
Subjects:
Pseudomonas aeruginosa
fluoroquinolone
antibiotic tolerance
transcription
stationary phase
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03567-23

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