Direct detection pays off for electron cryo-microscopy
Improved electron detectors and image-processing techniques will allow the structures of macromolecules to be determined from tens of thousands of single-particle cryo-EM images, rather than the hundreds of thousands needed previously.
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| Format: | Article |
| Language: | English |
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eLife Sciences Publications Ltd
2013-02-01
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| Series: | eLife |
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| Online Access: | https://elifesciences.org/articles/00573 |
| _version_ | 1828384308153286656 |
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| author | Nikolaus Grigorieff |
| author_facet | Nikolaus Grigorieff |
| author_sort | Nikolaus Grigorieff |
| collection | DOAJ |
| description | Improved electron detectors and image-processing techniques will allow the structures of macromolecules to be determined from tens of thousands of single-particle cryo-EM images, rather than the hundreds of thousands needed previously. |
| first_indexed | 2024-12-10T05:01:36Z |
| format | Article |
| id | doaj.art-47be4c8bb6b9446b9c55de477bbd5ea6 |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-12-10T05:01:36Z |
| publishDate | 2013-02-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-47be4c8bb6b9446b9c55de477bbd5ea62022-12-22T02:01:23ZengeLife Sciences Publications LtdeLife2050-084X2013-02-01210.7554/eLife.00573Direct detection pays off for electron cryo-microscopyNikolaus Grigorieff0Department of Biochemistry and the Howard Hughes Medical Institute, Brandeis University, Waltham, Untied StatesImproved electron detectors and image-processing techniques will allow the structures of macromolecules to be determined from tens of thousands of single-particle cryo-EM images, rather than the hundreds of thousands needed previously.https://elifesciences.org/articles/00573Electron microscopyImage processingT. thermophilusDirect electron detectorribosomeBayesian |
| spellingShingle | Nikolaus Grigorieff Direct detection pays off for electron cryo-microscopy eLife Electron microscopy Image processing T. thermophilus Direct electron detector ribosome Bayesian |
| title | Direct detection pays off for electron cryo-microscopy |
| title_full | Direct detection pays off for electron cryo-microscopy |
| title_fullStr | Direct detection pays off for electron cryo-microscopy |
| title_full_unstemmed | Direct detection pays off for electron cryo-microscopy |
| title_short | Direct detection pays off for electron cryo-microscopy |
| title_sort | direct detection pays off for electron cryo microscopy |
| topic | Electron microscopy Image processing T. thermophilus Direct electron detector ribosome Bayesian |
| url | https://elifesciences.org/articles/00573 |
| work_keys_str_mv | AT nikolausgrigorieff directdetectionpaysoffforelectroncryomicroscopy |